Results 141 to 150 of about 16,054,154 (327)

Efficacy and safety of empagliflozin for treating neutropenia and neutrophil dysfunction in paediatric patients with glycogen storage disease type Ib: A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk   +5 more
wiley   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić   +7 more
wiley   +1 more source

UK Web Archive Rebuild [Video]

open access: yes
Recording of a presentation provides an overview of how the UK Web Archive was affected following cyber-attacks in late October 2023, how the new operational technology landscape of the British Library changed, and describes the work being undertaken to ...
Hoggarth, Gil
core  

Safety concerns reported by coroners following fentanyl patch fatalities in England, Wales and Northern Ireland between 1997 and 2024

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim To identify safety concerns reported by coroners following fentanyl patch‐related deaths in England, Wales and Northern Ireland, and determine differences in coronial reporting. Methods A systematic case series linking the National Programme on Substance Use Mortality (NPSUM) and the Preventable Deaths Tracker (PDT) (https ...
Eman Mshari   +2 more
wiley   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum   +5 more
wiley   +1 more source

N‐acetylcysteine for non‐paracetamol‐induced acute liver failure in children: A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Non‐surgical treatment of acute liver failure (ALF) is primarily supportive and depends on the underlying cause. While N‐acetylcysteine (NAC) is proven effective in paracetamol‐induced ALF, its potential benefits in non‐paracetamol ALF for paediatric patients remain unclear.
Alise D. E. de Groot   +7 more
wiley   +1 more source

Los usuarios y las webs de los archivos históricos nacionales: el caso del Arquivo Nacional da Torre do Tombo (Portugal) Webs and national archives users: the case of Arquivo Nacional de Torre do Tombo (Portugal)

open access: yesInvestigación Bibliotecológica: Archivonomía, Bibliotecología e Información, 2009
El objetivo de este artículo es conocer cuál es la información o los servicios que se deberían incluir en el sitio web de un archivo, tomando como referencia la opinión de su público.
Amalia Más Bleda, Celia Chaín Navarro
doaj  

HyperJournal software, PHP scripting and Semantic Web technologies for the Open Access [PDF]

open access: yes, 2005
In this article we present an high level overview of the HyperJournal project, an effort to provide novel possibilities both in Scientific Publishing and in access to Scientific Contributions, according to the Open Access movement guidelines.
Barbera, Michele   +3 more
core  

Mobile health interventions to improve adherence to oral anticoagulant treatment: A systematic review and critical analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Non‐adherence to oral anticoagulants (OACs) is associated with significant morbidity and mortality. Mobile health (mHealth) interventions have been used to improve medication adherence across the three phases of initiation, implementation and persistence.
Non Davies   +2 more
wiley   +1 more source

NewsWARC: Analyzing News Over Time in the Web Archive [Presentation] [PDF]

open access: yes
Presentation highlighting NewsWARC, a tool, developed as an internship project, for aiding researchers to explore news content in a web archive collection over time. It was presented at the IIPC General Assembly and Web Archiving Conference held on April
Emara, Amr   +3 more
core  

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