Results 161 to 170 of about 16,054,154 (327)

Internet Archive

, 1996
The Internet Archive is building a digital library of Internet sites and other cultural artifacts in digital form. Like a paper library, we provide free access to researchers, historians, scholars, and the general public.
Internet Archive
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CYP3A5 genetic variability influences sildenafil and metabolite in pulmonary hypertension

British Journal of Clinical Pharmacology, EarlyView.
Aim Interindividual variability in sildenafil response among pulmonary hypertension patients (PH) may be influenced by CYP3A5 polymorphisms. CYP3A5*3 allele reduces CYP3A5 activity and affects sildenafil metabolism. This study investigated the associations between CYP3A5 genotype and plasma concentrations of sildenafil and N‐desmethyl sildenafil, as ...
Pranisa Wongwien, Burabha Pussadhamma, Sirimas Kanjanawart, Thikhumporn Areesinpitak, Nontaya Nakkam, Chingching Foocharoen, Wichittra Tassaneeyakul, Suda Vannaprasaht   +7 more
wiley   +1 more source

Unsupervised machine learning for multi‐system adverse event pattern detection in pharmacovigilance: A proof‐of‐concept analysis of fluoroquinolone reports in FAERS

British Journal of Clinical Pharmacology, EarlyView.
. Aims Traditional pharmacovigilance detects single drug–event associations but cannot readily characterize multi‐system adverse‐event patterns such as fluoroquinolone‐associated disability. We evaluated unsupervised machine learning for this purpose, using fluoroquinolones as an exemplar.
Niaz Chalabianloo, Sheikh S. Abdullah, Kamran Sedig, Flory T. Muanda   +3 more
wiley   +1 more source

The Korea Chemical Bank: Over 25 years of national chemical infrastructure alongside KRICT's 50‐year journey

Bulletin of the Korean Chemical Society, EarlyView.
This graphic abstract illustrates the role of the Korea Chemical Bank (KCB) as a central national hub that integrates government R&D, academic compound deposits, and industrial drug discovery throughout the latter half of KRICT's 50‐year history. Abstract Since its establishment in 2000 under the Korea Research Institute of Chemical Technology (KRICT),
Seul‐Gee Hwang, Su‐Min Kang, Soon Hee Hwang, Yuri Lee, Suyoun Lee, Ho‐Jin Kwon, Sunjong Yu, Soo Hee Kim, Eun Suk An, Sun Ho Kim, Sun Woo Kim, Hyeon Kyu Lee, Min Sung Kim, Seung Yeon Lee, Mali Prakash, Jaehyeon Park, Gehyeong Lee, Yuno Lee, Nam‐Chul Cho   +18 more
wiley   +1 more source

Building Towards Environmentally Sustainable Web Archiving: The UK Government Web Archive and Beyond [Video]

Recording of a presentation that discuss one approach to the development of a framework for more environmentally sustainable web archiving, using the UK Government Web Archive as a case study.
Goudarouli, Eirini, Bickford, Jake, Winters, Jane   +2 more
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What drives animal responses to high severity fire? The role of functional traits

Biological Reviews, EarlyView.
ABSTRACT Fire regimes are changing worldwide, with increases in the frequency, extent, and severity of fires posing growing risks to biodiversity. Fire severity – the degree of habitat alteration following fire – strongly influences both immediate survival and long‐term recovery of fauna.
Grace A. Vielleux, Trent D. Penman, Victoria A. Reynolds, Matthew H. Swan   +3 more
wiley   +1 more source

Investigation of the Currency, Disappearance and Half-Life of Urls of Web Resources Cited In Iranian Researchers: A Comparative Study

International Journal of Information Science and Management, 2018
This research was intended to comparatively investigate the currency, disappearance and half-life of URLs of web resources cited in Iranian researchers’ articles indexed in ISI in information science, psychology and management from 2009 to 2011.
Oranus Tajedini, ali Sadatmoosavi, Azita Ghazizade, Atefe Tajedini   +3 more
doaj  

Knowledge gaps and research directions in migration ecology for advancing the conservation of migratory songbirds

Biological Reviews, EarlyView.
ABSTRACT Understanding migration ecology is essential for effective conservation of migratory species. To achieve a comprehensive understanding of the ecology of migrating species, it is necessary to study how species react to the complex interplay of intrinsic and extrinsic conditions when optimizing their migratory journey in terms of survival ...
Daniel A. F. Bloche, Heiko Schmaljohann, Nir Sapir   +2 more
wiley   +1 more source

Under Construction: Web Archive of the German National Library [Video]

Recording of a presentation sharing the journey of the German National Library web archive towards the implementation of an in-house and open source web archiving system.
Arndt, Natanael
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Resolving the biome debate: ecological and palaeo‐data concur that the extensive tree‐limited grassy biomes of central and north‐western Madagascar are largely anthropogenic

Biological Reviews, EarlyView.
ABSTRACT For millennia, human activities have transformed ecosystems globally. Determining which landscapes are predominantly anthropogenic is crucial to conservation and habitat restoration. Madagascar, a critically‐threatened biodiversity hotspot, is a prominent example.
Grant S. Joseph, Sean Hixon, Colleen L. Seymour, Laurie R. Godfrey, Miguel Pedrono, Karen E. Samonds, Andrinajoro R. Rakotoarivelo, Brooke E. Crowley   +7 more
wiley   +1 more source