Results 21 to 30 of about 3,094,732 (188)
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
Silicon web process development [PDF]
Thirty-five (35) furnace runs were carried out during this quarter, of which 25 produced a total of 120 web crystals. The two main thermal models for the dendritic growth process were completed and are being used to assist the design of the thermal ...
Blais, P. D. +4 more
core +4 more sources
Co-operative authoring and collaboration over the World Wide Web : a thesis presented in partial fulfilment of the requirements for the degree of Master of Technology in Computer Systems Engineering at Massey University, Palmerston North, New Zealand [PDF]
, 2000 Co-operative authoring and collaboration over the World Wide Web is looking at a future development of the Web. One of the reasons that Berners-Lee created the Web in 1989 was for collaboration and collaborative design.
Hean, Daniel Robert
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FEBS Open Bio, EarlyView.We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli +15 more
wiley +1 more source
Technical Issues in the Development of Knowledge-Based Services for the Semantic Web [PDF]
, 2005 The Semantic Web aims to extend the current Web with formal semantics in order to improve how users experience the Web, by ameliorating current activities and supporting the automation of some others. So far, current Semantic Web prototypes mostly aim at
Bernaras, Amaia +2 more
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Web engineering security: essential elements [PDF]
, 2007 Security is an elusive target in today’s high-speed and extremely complex, Web enabled, information rich business environment. This paper presents the idea that there are essential, basic organizational elements that need to be identified, defined and ...
Glisson, W.B., Welland, R.
core +1 more source
FEBS Open Bio, EarlyView.Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki +11 more
wiley +1 more source
Professional Development On-line [PDF]
, 2002 Continuing Professional Development (CPD) is making increased use of the Web to develop and support communities of professionals. This paper outlines the factors driving the adoption of CPD and highlights areas where the Web can aid in the development of
Ferguson, J.D. +3 more
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