Results 61 to 70 of about 3,507,851 (336)

ODESWS, A Semantic Web Service Development [PDF]

, 2004
ODE SWS is a development environment to design Semantic Web Services (SWS) at the knowledge level. ODE SWS describe the service following a problem-solving approach in which the SWS are modeled using tasks, to represent the SWS functional features ...
González-Cabero, R., Gómez-Pérez, A., Lama, M.   +2 more
core   +1 more source

Semantic Transformation of Web Services [PDF]

, 2005
Web services have become the predominant paradigm for the development of distributed software systems. Web services provide the means to modularize software in a way that functionality can be described, discovered and deployed in a platform independent ...
A. Paar, C. Partridge, D. Fensel, J. Hendler, K. Sycara, S. Staab, S.A. McIllraith, T. Honderich, T.R. Gruber   +8 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

GENERATIVE AI-DRIVEN WEB DEVELOPMENT: A COMPREHENSIVE SYSTEMATIC REVIEW AND FUTURE RESEARCH DIRECTIONS

Tạp chí Khoa học
The rapid advancement of generative artificial intelligence is reshaping the field of web development, opening new possibilities for automated code generation and intelligent interface design.
Nguyen Thu Phuong*, Nguyen Thi Dung, Doan Ngoc Phuong
doaj   +1 more source

Open Source Web Platform for the Analysis of Academic Spin-offs

Journal of Information Systems Engineering and Business Intelligence, 2018
Universities have assumed an increasingly important role in transferring technology to society with a strong economic impact. The companies originated from the academic environment, called academic spin-offs, have fostered the appearance of new projects ...
Fernando Almeida, Eugénio Cunha
doaj   +1 more source

PENGEMBANGAN RUBI WEB (RUMAH BIOLOGI WEB) DALAM KONSEP KEANEKARAGAMAN HAYATI THE DEVELOPMENT OF RUBI WEB (RUMAH BIOLOGI WEB) IN BIODIVERSITY CONCEPT

Al-Ulum, 2022
This study aims to develop a web-based learning media, namely RUBI WEB (House of Biology Web) in the concept of biodiversity. The research method used in this research is a modified development research method from Borg & Gall whose stages consist of ...
Mahrawi Mahrawi, Indria Wahyuni, Dwi Ratnasari, Yunvida Istiana   +3 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source