Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao +2 more
wiley +1 more source
Sensor-Based Mobile App for Assessment and Tracking (SMAAT): Cross-Sectional Usability Study. [PDF]
Shevchenko Y, Hong H.
europepmc +1 more source
A CD14‐Targeting In Situ Hydrogel Directs Macrophage Reprogramming to Minimize Scar Formation
A CD14‐targeting in situ hydrogel formed from a microbial polysaccharide rapidly remodels the immune microenvironment by reprogramming macrophage polarization, suppressing excessive inflammation, and coordinating tissue regeneration. This multifunctional hydrogel promotes scar‐reduced wound repair through enhanced angiogenesis, collagen remodeling, and
Rui Fang +5 more
wiley +1 more source
CytokineProfile: An Integrated Web Tool for Cytokine Profiling Analysis. [PDF]
Saraswat S +4 more
europepmc +1 more source
Biosynthesis of Spatially Differentiated Cellulose for Flexible All‐in‐one Supercapacitors
Spatially differentiated bacterial cellulose is grown by oxygen‐guided biosynthesis to form dense surface regions connected by an open fibrillar interlayer. This architecture supports electroactive material loading, ion transport, and mechanical stability in an all‐in‐one supercapacitor, showing how biological assembly can create device‐ready ...
Xin Shu +7 more
wiley +1 more source
FAIR by design (TRACE): A Trusted Research Access & Collaboration Environment. [PDF]
Müller M +6 more
europepmc +1 more source
Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng +12 more
wiley +1 more source
Current practices in modelling dose-response relationships in network meta-analyses of depression treatments: a meta-research study. [PDF]
Herder KE, Liu Y, LaFleur B, Lin L.
europepmc +1 more source
Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy
A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao +10 more
wiley +1 more source
An interpretable predictive model for depression risk in diabetic patients: A web-based application using NHANES data. [PDF]
Li Y +9 more
europepmc +1 more source

