Results 31 to 40 of about 402,602 (294)
A Wolf May Change His Coat, but His Character?! - The New Web of Knowledge 5.0 Platform, and News Regarding the Web of Science Bibliography and Citation Database [PDF]
Web of Knowledge 5 ...
Macan, B.
doaj
The organization of knowledge: bibliometric study in database ISI Web of Knowledge
The Organization of Knowledge is an area of multiple applications and very traditional in research / teaching in Information Science. Most of the literature deals with the process, activities and tools specially developed for the treatment of documents ...
Cláudia Daniele de Souza
doaj +1 more source
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg+2 more
wiley +1 more source
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche+2 more
wiley +1 more source
Landscape of BRAF transcript variants in human cancer
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda+5 more
wiley +1 more source
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi+2 more
wiley +1 more source
On-To-Knowledge: Semantic Web-Enabled Knowledge Management [PDF]
On-To-Knowledge builds an ontology-based tool environment to improve knowledge management, dealing with large numbers of heterogeneous, distributed, and semistructured documents typically found in large company intranets and the World-Wide Web. The project’s target results are: (i) a toolset for semantic information processing and user access; (ii ...
Sure-Vetter, York+19 more
openaire +2 more sources
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki+11 more
wiley +1 more source
HOW NOT TO REJECT THE A PRIORI* [PDF]
According to one influential argument against the existence of a priori knowledge, there is no a priori knowledge because (i) no belief is immune to revision, and (ii) if there were a priori knowledge, at least some beliefs would be unrevisable.
Célia Teixeira
doaj +2 more sources
Identifying prognostic targets in metastatic prostate cancer beyond AR
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng+13 more
wiley +1 more source