Results 101 to 110 of about 3,346,481 (398)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Laboratory animals search filter for different literature databases: PubMed, Embase, Web of Science and PsycINFO

open access: yesLaboratory Animals. Journal of the Laboratory Animal Science Association, 2021
Systematic reviews are important tools in animal research, but the ever-increasing number of studies makes retrieval of all relevant publications challenging. Search filters aid in retrieving as many animal studies as possible.
S. van der Mierden   +5 more
semanticscholar   +1 more source

Discovering Rehabilitation trends in Spain: A bibliometric analysis [PDF]

open access: yes, 2019
The main purpose of this study is to offer an overview of the rehabilitation research area in Spain from 1970 to 2018 through a bibliometric analysis. Analysis of performance and a co-word science mapping analysis were conducted to highlight the topics ...
Cobo Martín, Manuel Jesús   +3 more
core   +1 more source

Identifying the Influential Latent Edges for Promoting the Co-SIR Model

open access: yesComplexity, 2021
The network-based cooperative information spreading is a widely existing phenomenon in the real world. For instance, the spreading of disease outbreak news and disease prevention information often coexist and interact with each other on the Internet ...
Dan Yang   +3 more
doaj   +1 more source

Are Papers Asking Questions Cited More Frequently in Computer Science?

open access: yesComputers, 2021
In this article, we test the hypothesis that computer science papers asking questions (i.e., those with a question mark at the end of their title) are cited more frequently than those that do not have this property.
Dalibor Fiala   +2 more
doaj   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

open access: yesFEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng   +13 more
wiley   +1 more source

Bibliometric Analysis on Research Trend of Accidental Falls in Older Adults by Using Citespace—Focused on Web of Science Core Collection (2010–2020)

open access: yesInternational Journal of Environmental Research and Public Health, 2021
The present study aimed to identify the trends in research on accidental falls in older adults over the last decade. The MeSH (Medical Subject Headings) and entry terms were applied in the Web of Science Core Collection.
Boyuan Chen, Sohee Shin
semanticscholar   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

open access: yesFEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

A Criteria-based Assessment of the Coverage of Scopus and Web of Science

open access: yesJournal of Data and Information Science, 2019
Purpose The purpose of this study is to assess the coverage of the scientific literature in Scopus and Web of Science from the perspective of research evaluation.
D. Aksnes, G. Sivertsen
semanticscholar   +1 more source

HotGrid: Graduated Access to Grid-based Science Gateways [PDF]

open access: yes, 2004
We describe the idea of a Science Gateway, an application-specific task wrapped as a web service, and some examples of these that are being implemented on the US TeraGrid cyberinfrastructure.
Bunn, Julian   +2 more
core  

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