Results 51 to 60 of about 756,623 (284)

Experimental Study of Ultra Shallow Floor Beams (USFB) with Perforated Steel Sections [PDF]

, 2009
: In modern building construction design, floor spans are becoming longer. Hence, steel framed structures have become more competitive when compared with traditional reinforced concrete framed buildings. In order to minimise the structural section of the
D'Mello, C., Hawes, M., Tsavdaridis, K. D.   +2 more
core  

Web OPEN-Integrated: Proposed Framework for Web Development [PDF]

, 2005
Most Web applications are designed in an ad-hoc manner. Web applications, due to their peculiar nature, cannot be just developed as conventional software projects. Haire et al advocate Web OPEN [1] [2], extension to OPEN (Object-oriented Process, Environment, and Notation), as suitable model and provide a good study on it.
Rashid Ahmad, Zhang Li, Farooque Azam
openaire   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Numerical study of web crippling strength in cold-formed austenitic stainless steel lipped channels with web openings subjected to interior-two-flange loading [PDF]

, 2016
In cold-formed stainless steel lipped channel-sections, use of web openings for service purposes are becoming increasingly popular. Web openings, however, result in the sections becoming more susceptible to web crippling.
Clifton, G. C., Lim, J. B.P., Uzzaman, A., Young, B., Yousefi, A. M.   +4 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Finite Element Analysis of Lateral Torsional Buckling Behaviour of Tapered Steel Section with Perforation

MATEC Web of Conferences, 2016
This paper presents the finite element analysis of lateral torsional buckling of tapered steel section with perforation. The numerical analysis consists of four main models with a ratio of tapering 0.3 for 3.5m and 5.5m span and ratio of tapering 0.5 for
Naaim Nurfarhah, De’nan Fatimah, Keong Choong Kok, Azar Faiz   +3 more
doaj   +1 more source

The Relevance of Open Data Principles for the Web of Data

Journal of Electrical and Computer Engineering, 2023
Open data has been improving both publishing platforms and the consumers-oriented process over the years, providing better openness policies and transparency. Although organizations have tried to open their data, the enrichment of their resources through
Jhon Francined Herrera-Cubides, Paulo Alonso Gaona-García, Carlos Enrique Montenegro-Marin, Salvador Sánchez-Alonso   +3 more
doaj   +1 more source

Automated Detection of Non-Relevant Posts on the Russian Imageboard "2ch": Importance of the Choice of Word Representations

, 2017
This study considers the problem of automated detection of non-relevant posts on Web forums and discusses the approach of resolving this problem by approximation it with the task of detection of semantic relatedness between the given post and the opening
Bakarov, Amir, Gureenkova, Olga
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source