Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Opening Closed Doors: A Rationale for Creating a Safe Space for Tutors Struggling with Mental Health Concerns or Illnesses [PDF]
Because writing centers exist to help students find success in academia—to enter doors that may otherwise be closed to them—writing center literature rightly discusses the need to work with students of all backgrounds and abilities (Pemberton; Neff ...
Degner, Hillary +2 more
core +1 more source
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Web crippling design of cold-formed duplex stainless steel lipped channel-sections with web openings under end-one-flange loading condition [PDF]
Cold-formed stainless steel sections are becoming more widely used in the residential and commercial sectors due to their high corrosion resistance and high strength-to-weight ratio.
Clifton, G.C. +5 more
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Librarians use of Web 2.0 in UK Medical Schools: Outcomes of a national survey [PDF]
Using the results of an Email survey, this paper reviews the use of Web 2.0 technologies by librarians working in UK Medical Schools. Web 2.0 has been hailed as an innovation for facilitation of two way communication on the net, and it is, therefore ...
Grant, V, Kuhn, I, Pacheco, J
core +1 more source
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
To be or not to be, the importance of Digital Identity in the networked society [PDF]
The emergence of the web has had a deep impact at different levels of our society, changing the way people connect, interact, share information, learn and work.
Costa, Cristina, Torres, Ricardo
core +1 more source
E-reference: incorporating electronic publications into reference [PDF]
The traditional work of reference librarians has been greatly impacted by access to electronic publications on the World Wide Web. Reference librarians are also using the Web to create electronic publications for in-library users and Web surfers.
Diaz, Karen R., Young, Courtney L.
core +1 more source
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Finite Element Investigation on Web-Post Buckling of Perforated Steel Beams with Various Web Opening Shapes subjected under different shear-moment interaction [PDF]
The current method of assessment is based on FE models which still lack computational efficiency and are restricted by a number of limitations. Therefore, this work aims at the feasibility of developing FE models which are applicable to deformation and ...
D'Mello, C., Tsavdaridis, K. D.
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