Results 171 to 180 of about 4,303,222 (336)

Computational Design and Glycoengineering of Interferon‐Lambda for Nasal Prophylaxis Against Respiratory Viruses

Advanced Science, EarlyView.
This study presents an engineered human interferon‐lambda (hIFN‐λ) as an intranasal prophylactic against respiratory viruses. By combining AI‐guided backbone redesign and glycoengineering, the authors developed a thermostable, protease‐resistant, and scalable variant with improved mucosal penetration.
Jeongwon Yun, Seungju Yang, Jae Hyuk Kwon, Luiz Felipe Vecchietti, Ji Hyun Choi, Mi‐ra Choi, Keun Bon Ku, Hyun‐Joo Ro, Kyun‐Do Kim, Meeyoung Cha, Hyun Jung Chung, Ji Eun Oh, Ho Min Kim   +12 more
wiley   +1 more source

Tracking Public Interest in Rare Diseases and Eosinophilic Disorders in Germany: Web Search Analysis. [PDF]

JMIR Infodemiology
Hindelang M, Sitaru S, Zink A.
europepmc   +1 more source

An architecture for non-linear discovery of aggregated multimedia document web search results. [PDF]

PeerJ Comput Sci, 2021
Khan AR, Rashid U, Rashid U, Saleem K, Ahmed A.   +4 more
europepmc   +1 more source

How do consumers search for and appraise health information on the world wide web? Qualitative study using focus groups, usability tests, and in-depth interviews

British medical journal, 2002
G. Eysenbach, C. Köhler
semanticscholar   +1 more source

Strong Proton‐Phonon Coupling Drives Fast Ion Transport in Perovskites

Advanced Science, EarlyView.
Experimental and computational phonon analysis of ABO3‐type proton conductor BaSnO3 shows that substitution on the B‐site with yttrium forms an imaginary phonon mode which is instrumental for the function as proton conductor. This overcompensates the adverse proton trapping effect of the yttrium.
Alexey Rulev, Nobumoto Nagasawa, Hongxin Wang, Vladimir Pomjakushin, Martin Kunz, Yoshitaka Yoda, Stephen P. Cramer, Qianli Chen, Artur Braun   +8 more
wiley   +1 more source

Struggling and Success in Web Search

International Conference on Information and Knowledge Management, 2015
Daan Odijk, Ryen W. White, Ahmed Hassan Awadallah, S. Dumais   +3 more
semanticscholar   +1 more source

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier

Advanced Science, EarlyView.
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao, Aiting Wang, Yue Xu, Wenxin Feng, Chunxiao Ma, Ziyi Wang, Wei Zhang, Wenqiong Su, Xiuying Xiao, Wei‐Qiang Gao, Xianting Ding, Li Li   +11 more
wiley   +1 more source

Swedish news search engines on the Web : An evaluation of Yahoo! News and Sesam’s retrieval effectiveness

, 2007
Sigurd, Therese
openalex   +1 more source

Protein Language Model‐Guided Engineering of a 2,3‐Butanediol Dehydrogenase for the Enantioselective Synthesis of Cyclic α‐Hydroxy Ketones

Advanced Science, EarlyView.
A (2R,3R)‐butanediol dehydrogenase from Bacillus subtilis (BsBDH) is engineered for the enantioselective synthesis of 2‐hydroxycyclohexanone. A PASS computational design strategy is proposed to enhance the thermostability of BsBDH. Moreover, ESM‐1v combined with ISM is utilized for enhancing and inverting its stereoselectivity.
Haote Ding, Ling Jiang, Yijia Song, Zhongji Pu, Lirong Yang, Haoran Yu   +5 more
wiley   +1 more source

Seasonal and Weekly Patterns of Korean Adolescents' Web Search Activity on Insomnia: Retrospective Study. [PDF]

JMIR Form Res
Baek K, Jeong J, Kim HW, Shin DH, Kim J, Lee GH, Cho JW.   +6 more
europepmc   +1 more source