Results 101 to 110 of about 262,860 (265)

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

User-Adapted Web Services by Extending the eIDAS Specification with Functional Attributes. [PDF]

Int J Environ Res Public Health, 2021
Marco L, Pozo A, Huecas G, Quemada J, Alonso Á.   +4 more
europepmc   +1 more source

High‐Throughput Data Generation and Transfer Learning Enabled Microstructure‐Property Integrated Design of Nickel‐Based Powder Metallurgy Superalloy

Advanced Science, EarlyView.
An integrated transfer learning framework integrates CALPHAD simulations, diffusion‐multiple experiments, and literature data to predict long‐term microstructural stability and short‐term mechanical properties of Ni‐based powder metallurgy superalloys. Based on these model predictions, a high‐performance, low‐density alloy, USTB‐PM750, is designed from
Zixin Li, Hongtao Zhang, Zichao Peng, Yuheng Zhang, Qian Lv, Yihuan Cao, Xuqing Wang, Huadong Fu, Jianxin Xie   +8 more
wiley   +1 more source

NGScloud2: optimized bioinformatic analysis using Amazon Web Services. [PDF]

PeerJ, 2021
Mora-Márquez F, Vázquez-Poletti JL, López de Heredia U.   +2 more
europepmc   +1 more source

A High‐Throughput Live Imaging Platform to Investigate Circuit‐Dependent Regulation of Circadian Rhythms in Brain Tissue

Advanced Science, EarlyView.
Biological rhythms coordinate physiology, from genes to behavior. Study of circadian rhythms in brain tissue is constrained by limited throughput and spatial and temporal information quality. A new platform for high‐throughput, long‐term multiplexed fluorescent live imaging of circadian rhythms in brain slices is introduced.
Marco Ferrari, Natalie Ness, Julieta Acosta, Marco Brancaccio   +3 more
wiley   +1 more source

Cutoff Grade Optimization on Operative Decision Variables with Geological Uncertainty in an Underground Gold Mine: A Real Case Study

Mathematics
In mine planning, uncertainty assessment is essential to properly value a mining project. Geological, operational, and economical risks have to be considered to find the variable values that maximize the profit of the project.
Diego Alejandro Toro Morales, Giovanni Franco Sepúlveda, Erick de la Barra, Juan Camilo Del Río Cuervo   +3 more
doaj   +1 more source

Knowledge Beacons: Web services for data harvesting of distributed biomedical knowledge. [PDF]

PLoS One, 2021
Hannestad LM, Dančík V, Godden M, Suen IW, Huellas-Bruskiewicz KC, Good BM, Mungall CJ, Bruskiewich RM.   +7 more
europepmc   +1 more source

DMS‐MaPseq and DREEM Analyses Implicate the Critical Role of RNA Structural Dynamics in Turnip Yellow Mosaic Virus Pathogenicity

Advanced Science, EarlyView.
RNA structural profiling of Turnip Yellow Mosaic Virus by DMS‐MaPseq and DREEM analyses uncover that viral genome‐wide RSS is highly complicated and heterogeneous, with alternative RSSs widely distributed across the genome. Notably, the viral 3’ tRNA‐like structure adopts alternative conformations in vivo.
Jiaying Zhu, Changhao Li, Chisimbily Onyia, Xindi Li, Xingxing Yan, Songxiao Zhong, Taerin Oh, Xiuren Zhang   +7 more
wiley   +1 more source

Trophic Diversity in Duckweed: Mixotrophy, More Than the Sum of its Extremes

Advanced Science, EarlyView.
In the context of rising DOC in aquatic environments, mixotrophic duckweed may impact carbon cycling by acting as either a carbon sink, as they absorb CO2 through photosynthesis, or a carbon source, as they release CO2 through respiration of absorbed DOC, which depends on DOC concentration, light availability, temperature, and other environmental ...
Zuoliang Sun, Yan Chen, Fajun Li, Xuyao Zhao, Qingxiang Han, Hongwei Hou   +5 more
wiley   +1 more source

RLSR: A Reinforcement Learning-Based Segment Routing for QoS-Aware Software-Defined Network

IEEE Transactions on Machine Learning in Communications and Networking
Traffic routing is crucial for the efficient operation of the Internet. As network traffic grows, adaptive and intelligent routing algorithms are needed to meet various Quality of Service (QoS) requirements.
Wang Wumian, Sajal Saha, Anwar Haque, Greg Sidebottom   +3 more
doaj   +1 more source