Results 31 to 40 of about 304,540 (265)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

LE PSEUDONYME : REFLET D’IDENTITE SUR LE WEB SOCIAL ? [PDF]

Studii de gramatică contrastivă, 2020
Cet article présente une réflexion sur l’identité et ses diverses formes de manifestations sur les plateformes socionumériques. Il ne sera pas ici question de traiter l’identité numérique dans sa totalité, mais il s’agira plutôt, pour nous, de nous ...
Achour Bourdache, Soufiane Lanseur
doaj  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

From e-commerce to s-commerce: Innovation within the reach of organizations. A study for footwear sector in Bucaramanga, Colombia

Contabilidad y Negocios: Revista del Departamento Académico de Ciencias Administrativas, 2017
Organizations perceive electronic commerce, as a mechanism to reach their stakeholders directly, facilitating the success of the transaction and from anywhere in the world (Guzman, Gil & Carot 2013).
Alba Patricia Guzmán Duque, Carlos Alberto Abreo Villamizar   +1 more
doaj  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Hacia una web social libre y federada: el caso de Lorea

Revista Teknokultura, 2012
Este artículo aborda las limitaciones de la web 2.0, las claves para superarlas y las recientes iniciativas de web social libre y federada. De entre ellas nos centraremos en el caso de Lorea desde nuestra experiencia directa con ella.
Florencio Cabello, Marta G. Franco, Alex Haché   +2 more
doaj   +2 more sources

Googling social interactions: web search engine based social network construction. [PDF]

PLoS ONE, 2010
Social network analysis has long been an untiring topic of sociology. However, until the era of information technology, the availability of data, mainly collected by the traditional method of personal survey, was highly limited and prevented large-scale ...
Sang Hoon Lee, Pan-Jun Kim, Yong-Yeol Ahn, Hawoong Jeong   +3 more
doaj   +1 more source

Permuting Web and Social Graphs [PDF]

Internet Mathematics, 2009
Abstract Since the first investigations on web-graph compression, it has been clear that the ordering of the nodes of a web graph has a fundamental influence on the compression rate (usually expressed as the number of bits per link). The authors of the LINK database [Randall et al.
P. Boldi, M. Santini, S. Vigna
openaire   +2 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source