Results 111 to 120 of about 659,210 (249)
Advanced Science, EarlyView.Arsenic in realgar induces CNS toxicity through direct and indirect effects: it activates ZBTB7A in astrocytes, which in turn inhibits glycolysis and impairs mice's learning, memory, and exploration; it also suppresses OTC in the liver to block the ornithine cycle, leading to blood ornithine accumulation that crosses into the frontal lobe and further ...
Ping Ye +7 more
wiley +1 more source
Egg Donation Brokers: An Analysis of Agency Versus in Vitro Fertilization Clinic Websites
, 2014 Eve Holwell +4 more
openalex +1 more source
Web requests analysis of Italy websites which use Google Analytics
, 2022 Federico Leva
openalex +2 more sources
Building an Expert System through Machine Learning for Predicting the Quality of a Website Based on Its Completion [PDF]
, 2023 Sastry Kodanda Rama Jammalamadaka +4 more
openalex +1 more source
Advanced Science, EarlyView.This study reveals that Arabidopsis telomere repeat binding proteins (TRBs) form two closely related complexes. These complexes mediate H3K4me3 demethylation and transcriptional repression through a positive feedback loop and cooperate with PEAT and PRC2 complexes to regulate multiple histone modifications and gene expression across the genome ...
Qi Wang +7 more
wiley +1 more source
Advanced Science, EarlyView.This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang +15 more
wiley +1 more source
Advanced Science, EarlyView.Single‐nucleus RNA sequencing of mid‐gestation brains from fetuses with nonsyndromic cleft lip and palate reveals major disruptions in cell composition, cell‐to‐cell signaling, and gene regulation. The transcription factor MEF2C is identified as a central regulator of these changes and shows that lowering MEF2C impairs synapse formation, linking cleft ...
Liu‐Lin Xiong +19 more
wiley +1 more source
Advanced Science, EarlyView.This study demonstrates that vinburnine, an approved cerebrovascular drug, synergizes with radiotherapy in nasopharyngeal carcinoma (NPC) by modulating EDAR‐NFκB signaling through directly binding to EDAR, leading to triggering apoptosis/pyroptosis, and amplifying CCL5/CX3CL1‐driven T‐cell cytotoxicity.
Jing Chen +9 more
wiley +1 more source
Enhancing Saudi EFL Learners’ CAF in Narrative Writing Through Native Speaker Kids’ Reading Website
, 2020 Talal Musaed Alghizzi +1 more
openalex +1 more source