Results 131 to 140 of about 578,031 (253)

A qualitative exploration of the barriers and facilitators for engagement with a self-led biopsychosocial support tool, Pain Rehabilitation to Optimize Major Orthopaedic Trauma REcovery (PROMOTE), for patients with complex lower-limb orthopaedic trauma. [PDF]

Bone Jt Open
Fordham B, Tutton E, Painton R, Gould J, Achten J, Costa ML, Keene DJ.   +6 more
europepmc   +1 more source

AARS1‐Mediated RUNX3 K193 Lactylation Enhances the Activation and Cytotoxicity of CD8+T Cells in Smoking‐Related Emphysema

Advanced Science, EarlyView.
Exposure to CS causes an elevation of AARS1 levels, which increases the levels of RUNX3 lactylation at the K193 site and increases protein levels of RUNX3 through inhibition of autolysosomal degradation. Elevated RUNX3 levels promote CD8+T cell activation and augment their cytotoxicity, which induces alveolar epithelial cell death and facilitates the ...
Ying Zhu, Jiaheng Lin, Yifan Li, Qiaoqiao Zhou, Min Yu, Cheng Cheng, Kang Chang, Dang Lin, Tao Bian, Yan Wu, Lu Lu, Haibo Xia, Qizhan Liu   +12 more
wiley   +1 more source

TSTScope Unifies Single‐Cell Multi‐Omics to Identify Functional T Cell States Predictive of Immunotherapy Response

Advanced Science, EarlyView.
TSTScope is an interpretable AI framework that integrates single‐cell transcriptomes with TCR information through curated gene‐program constraints. By linking receptor context to functional T cell states, it reveals response‐associated tumor‐specific T cell programs in lung cancer immunotherapy cohorts and defines an MPR score associated with ...
Shiwei Cao, Jinyu Cheng, Feng‐ao Wang, Chenxin Yi, Jiajun Chen, Keyue Wang, Lulu Liu, Junwei Liu, Yixue Li   +8 more
wiley   +1 more source

Program Analisis Frekuensi Besaran Rancangan Berbasis Website

Jurnal Teknik Sipil
Abstrak Rancangan bangunan air memiliki perhitungan yang panjang. Analisis frekuensi merupakan salah satu dari perhitungan tersebut. Teknologi yang telah berkembang perlu dimanfaatkan guna mempermudah proses perhitungan tersebut. Sebuah website adalah
Ginanjar Dwi Prasetyo, Nizar Achmad, Titiek Widyasari   +2 more
doaj  

Development and Evaluation of a German Suicide Prevention Website for Men: Exploratory Study. [PDF]

JMIR Form Res
Spahn C, Dobroschke JG, Spangenberg L, Glaesmer H.   +3 more
europepmc   +1 more source

Safety of Sodium‐Ion Batteries: Evaluation and Perspective from Component Materials to Cells, Modules, and Packs

Advanced Energy Materials, EarlyView.
This review provides a bottom‐up evaluation of sodium‐ion battery safety, linking material degradation mechanisms, cell engineering parameters, and module/pack assembly. It emphasizes that understanding intrinsic material stability and establishing coordinated engineering control across hierarchical levels are vital for preventing degradation coupling ...
Won‐Gwang Lim, Seoa Kim, Erik A. Wu, Darren H. S. Tan, Shawn Peng, Xiaolin Li   +5 more
wiley   +1 more source

A critical analysis of online social support websites for Australians seeking bariatric surgery. [PDF]

Aust J Psychol
Stewart R, Chur-Hansen A.
europepmc   +1 more source

Accounting for Substitution: Improving Estimates of GHG Reductions From Cattle‐Based Product Demand Shifts

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Estimates of reductions in greenhouse gas (GHG) emissions from lower demand for cattle‐based products must account for substitution effects. This study collected data through two surveys—one on ground beef and another on dairy milk—to evaluate substitution effects and potential GHG reductions.
Brandon R. McFadden, Sara Gardner Hedgecock, Lawton L. Nalley, Alvaro Durand‐Morat, Aaron Shew, Rodolfo M. Nayga Jr   +5 more
wiley   +1 more source

Temperature Sensitivity and Adaptation of Cereal Yields: Empirical Evidence From Italy

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT This paper investigates the evolving temperature sensitivity and climate adaptation of cereal yields in Italy from 1952 to 2023, using province‐level data for maize, common wheat, and durum wheat. Employing panel data econometric methods, we estimate yield responses to heat exposure, changes in sensitivity over time, and adaptation to climate ...
Paolo Nota, Giacomo Coughlan, Alessandro Olper   +2 more
wiley   +1 more source

From patients to partners: evaluating a co-designed website for congenital hypogonadotropic hypogonadism. [PDF]

Endocr Connect
Dwyer AA, Smith N, Strasser S, Keels JN, McDonald IR, Chi J, Le R.   +6 more
europepmc   +1 more source