Results 161 to 170 of about 670,585 (273)
Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen +11 more
wiley +1 more source
Is Online Oriented-Centred Information About Dry Mouth Trustworthy? An Infodemiologic Study. [PDF]
Alassaf M +7 more
europepmc +1 more source
Gabpα‐Pparγ Complex Determines Glycolytic Capacity and Lactic Acid Homeostasis in Brown Fat
This study identifies the Gabpα–Pparγ complex as a key transcriptional regulator that couples glycolysis to lactate‐driven thermogenesis in brown adipose tissue by directly activating Eno1 transcription. Competitive disruption of this interaction impairs lactate metabolism and thermogenic capacity.
Zhihan Wang +22 more
wiley +1 more source
CeSTAAN: An atlas of <i>C. elegans</i> adult neurons for fast queries of single-nucleus RNA sequencing data. [PDF]
St Ange J, Langmack H, Murphy CT.
europepmc +1 more source
CACLENS: A Multitask Deep Learning System for Enzyme Discovery
CACLENS, a multimodal and multi‐task deep learning framework integrating cross‐attention, contrastive learning, and customized gate control, enables reaction type classification, EC number prediction, and reaction feasibility assessment. CACLENS accelerates functional enzyme discovery and identifies efficient Zearalenone (ZEN)‐degrading enzymes.
Xilong Yi +5 more
wiley +1 more source
Building Your Best Day: Disseminating the Canadian 24-Hour Movement Guidelines for Children and Youth via an Interactive Website. [PDF]
Gierc M +5 more
europepmc +1 more source
MushroomExpert.Com website [website review]
openaire +2 more sources
His‐MMDM: Multi‐Domain and Multi‐Omics Translation of Histopathological Images with Diffusion Models
His‐MMDM is a diffusion model‐based framework for scalable multi‐domain and multi‐omics translation of histopathological images, enabling tasks from virtual staining, cross‐tumor knowledge transfer, and omics‐guided image editing. ABSTRACT Generative AI (GenAI) has advanced computational pathology through various image translation models.
Zhongxiao Li +13 more
wiley +1 more source

