Results 191 to 200 of about 659,210 (249)

5′tRF‐GlyGCC Promotes Breast Cancer Progression via LDHA‐Mediated Glycolysis and Macrophage Polarization

Advanced Science, EarlyView.
5’tRF‐GlyGCC promotes breast cancer malignancy by binding to LDHA. This interaction, facilitated by FGFR1 and LDHA phosphorylation, enhances glycolysis. Additionally, 5’tRF‐GlyGCC/LDHA signaling recruits and polarizes macrophages into a pro‐tumor M2 state via CCL7, thus remodeling the tumor microenvironment.
Cheng Yi, Yunqing Lu, Xing Chang, Ying Wang, Jiawang Zhou, Guoyou Xie, Lijun Tao, Zhaotong Wang, Yifan Tian, Lihong Wang, Feng Tang, Yijing Zheng, Xinchen Yue, Jinping Lei, Xiansong Wang, Lichen Ge, Zhuojia Chen, Hongsheng Wang   +17 more
wiley   +1 more source

Evaluating the Readability and Understandability of Online Patient Materials Regarding Balloon Sinuplasty. [PDF]

OTO Open
Bhalla SR, Bancalari LE, Shaari AL, McCormick JP.   +3 more
europepmc   +1 more source

Population‐Based Multi‐Omics and Cohort Study Identifying Predictive Biomarkers and Therapeutic Targets for Psoriatic Disease

Advanced Science, EarlyView.
Psoriatic disease (PsD) is a chronic skin disease, with challenges in early risk stratification and drug development. Through gene‐level causal inference framework and expression level validation, combined with longitudinal cohort study, CDSN and PRSS8 have been identified as candidate biomarkers and therapeutic targets for PsD.
Tianxing Wu, Jialiang Luo, Haoyuan Qiu, Weijie Shao, Yueyang Lu, Meixuan Luo, Zhaofeng Lin, Yan Zhang, Libo Zhang, Hong Wang, Jia Zhou, Guangfeng Ruan, Peihua Cao, Daming Zuo   +13 more
wiley   +1 more source

Pizza and Paintballs: A Cost-Effective Model for Incision and Drainage Simulation Training. [PDF]

J Educ Teach Emerg Med
McNeal P, Boan AD, Douglas E.
europepmc   +1 more source

WebTrackingScore: A Combined Web Tracking Risk Score System for Websites [PDF]

A. Cava, Antonio Ruiz‐Martínez
openalex   +1 more source

Insect I‐Type Lysozymes Function as Antiviral Proteases by Forming Biomolecular Condensates

Advanced Science, EarlyView.
Upon rice viral infection, the insect vector activates the Toll–MyD88–Dorsal signaling cascade, inducing i‐type lysozyme (Lyz‐I1) expression. Lyz‐I1 functions as an antiviral protease through its conserved catalytic dyad Glu/Asp (E/D), mediating cleavage of viral proteins at specific Lys (K) residues.
Yu Du, Yuqing Xiao, Manman Hu, Jinhua Yang, You Li, Taiyun Wei   +5 more
wiley   +1 more source

Identifying behavior mediators influencing caregivers of infants participating in an mhealth intervention: qualitative evaluation of the Baby-Feed trial through interviews. [PDF]

Mhealth
Gatto A, Moore M, Hannan J, Palacios C.
europepmc   +1 more source

Optimalisasi Website Desa Sebagai Media Iinformasi dan Inovasi di Desa Mertak Kab. Lombok Tengah

Sonia Tarandari, Maulana Ashari
openalex   +2 more sources

scPER: A Rigorous Computational Approach to Determine Cellular Subtypes in Tumors Aligned With Cancer Phenotypes From Total RNA Sequencing

Advanced Science, EarlyView.
scPER presents an adversarial‐autoencoder framework that deconvolves bulk total RNA‐seq to quantify tumor‐microenvironment cell types and uncover phenotype‐linked subclusters. Across diverse benchmarks, scPER improves accuracy over existing tools.
Bingrui Li, Xiaobo Zhou, Raghu Kalluri
wiley   +1 more source

Do the interpersonal effects of gamified online destination websites better stimulate tourists' travel intentions? [PDF]

PLoS One
Wang H, Qu M, Liu Y, Li W.
europepmc   +1 more source