Results 91 to 100 of about 53,779 (263)

THE ENVIRONMENTAL ATLAS OF THE CORUMBATAI WATERSHED - SP, BRAZIL

open access: yesRevista Brasileira de Cartografia, 2009
The Corumbatai watershed (1.710 km2 ) in the State of São Paulo - Brazil, is a well known region, mainly because one of the branches of the São Paulo State University - UNESP is located there, where most of the departments are related on environmental ...
Gilberto J. Garcia   +2 more
doaj  

Comprehensive analyses of the ARF gene family in cannabis reveals their potential roles in regulating cannabidiol biosynthesis and male flower development

open access: yesFrontiers in Plant Science
BackgroundCannabidiol (CBD), as an important therapeutic property of the cannabis plants, is mainly produced in the flower organs. Auxin response factors (ARFs) are play a crucial role in flower development and secondary metabolite production.
Gen Pan   +7 more
doaj   +1 more source

Towards a Compositional Framework for Describing Human Phenotypes

open access: yesAdvanced Science, EarlyView.
The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu   +11 more
wiley   +1 more source

A Metabolic‐Epigenetic Axis of AARS1/IGF2BP3‐K280 Lactylation Sustains Endometrial Cancer Stemness and Recurrence

open access: yesAdvanced Science, EarlyView.
Lactate‐driven endometrial cancer relapse is mediated by enzymatic protein modification. Elevated lactate levels activate AARS1, which catalyzes K280 lactylation of IGF2BP3, therefore stabilizing HMGA2 mRNA and promoting tumor stemness and recurrence.
Peng Jiang   +11 more
wiley   +1 more source

SAV1 in Cooperation With FKBP52 Participates in Implantation

open access: yesAdvanced Science, EarlyView.
The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao   +10 more
wiley   +1 more source

Cloning of AcRCI2A Gene from Pineapple and Its Expression Analysis in Blackheart Disease Resistance Treatment

open access: yesGuangdong nongye kexue
【Objective】To clone the rare cold-induced 2 gene (AcRCI2A) in pineapple and explore its expression in pineapple resistance to blackheart disease, laying the foundation for genetic improvement of blackheart disease resistance of pineapple fruit by this ...
Kanghua SONG, Keqian HONG, Hui GU
doaj   +1 more source

The MoSR‐MoDde1 Regulatory Axis: A Novel Determinant of DMI Sensitivity and a Target for Sustainable Rice Blast Control

open access: yesAdvanced Science, EarlyView.
The transcription factor MoSR governs DMI fungicide sensitivity in Magnaporthe oryzae through dual regulation of ergosterol biosynthesis and the detoxification enzyme MoDde1. Targeting MoDde1 via a small‐molecule inhibitor or host‐induced gene silencing enhances DMI efficacy against rice blast, offering a sustainable disease management strategy ...
Fan‐Zhu Meng   +10 more
wiley   +1 more source

PIFiA: self-supervised approach for protein functional annotation from single-cell imaging data

open access: yesMolecular Systems Biology
Fluorescence microscopy data describe protein localization patterns at single-cell resolution and have the potential to reveal whole-proteome functional information with remarkable precision.
Anastasia Razdaibiedina   +9 more
doaj   +1 more source

CHD8‐Dependent Chromatin Licensing Sustains Trophoblast Stem Cell Transcriptional Programs

open access: yesAdvanced Science, EarlyView.
In this study, Huang et al., identify chromatin remodeler CHD8 as an essential factor in TSC maintenance and placental development. CHD8‐dependent chromatin accessibility supports the occupancy of key trophoblast TFs and is coupled to KMT2A‐associated H3K4me3 deposition at TSC stem and cell cycle genes, providing a permissive chromatin environment for ...
Yuanyuan Huang   +16 more
wiley   +1 more source

A synthesis-based mapping of the landscape of neurodegenerative diseases

open access: yesNeuroImage
Neurodegenerative diseases (NDDs) exhibit heterogeneous patterns of anatomical involvement and cognitive impairment, yet a unified, brain-wide comparison across disorders is lacking.
Chanidapa Winalai, Dominique J. Bicout
doaj   +1 more source

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