Results 121 to 130 of about 1,242,519 (279)
Advanced Science, EarlyView.IGF1R is highly expressed in the armored & cold tumors, and collagen mediates IGF1R at the transcriptional and post‐translational levels to promote TNBC cell invasion and immune escape and to stabilize its own structure by interacting with the collagen receptor DDR1.
Mengyun Wan +8 more
wiley +1 more source
Advanced Science, EarlyView.This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie +8 more
wiley +1 more source
Advanced Science, EarlyView.This study develops enucleated MSC‐derived microvesicles (Mito@euMVs) to deliver functional mitochondria for optimizing wound repair. By efficiently encapsulating mitochondria, Mito@euMVs rejuvenate hyperglycemia‐induced senescent fibroblasts and HUVECs. Using PVA microneedle patches, the therapeutic efficacy of Mito@euMVs is validated in diabetic rats
Zixuan Dong +3 more
wiley +1 more source
Advanced Science, EarlyView.Root‐knot nematode (RKN) disease seriously affects the yield and quality of vegetable crops. SlDOF9‐SlSWEET17 model helps plants resist RKN infection during early stage by switching off the sugar transport capacity of other SlSWEET proteins that are hijacked by RKNs.
Xiaoyun Wang +14 more
wiley +1 more source
Accessibility of Websites for People with Disabilities (PWD) in Malaysia: An Empirical Investigation
, 2011 Maslina Abdul Aziz +2 more
openalex +2 more sources
Web accessibility evaluation of university websites in turkey in terms of visually and hearing impaired users [PDF]
, 2019 Halise Serefoglu, Türkay Henkoğlu
openalex +1 more source
Advanced Science, EarlyView.Novel ATR/PARP1 dual inhibitors are developed for the first time. Advanced lead B8 effectively reduces cell viability in vitro and suppresses tumor growth in vivo, with better potency than ATRi and PARPi alone or in combination. Mechanistically, B8 induces apoptosis, arrests the cell cycle, and inhibits cancer cells colony formation, migration, and ...
Yuan Gao +13 more
wiley +1 more source