Results 141 to 150 of about 95,019 (268)

Pruning Blockchain Protocols for Efficient Access Control in IoT Systems [PDF]

open access: yesarXiv
We consider access control for IoT systems that involves shared accesses to the IoT devices as well as their data. Since IoT devices are dispersed all over the edge of the Internet, traditional centralized access control has problems. Blockchain based decentralized access control is thus the new solution trend. However, existing blockchain based access
arxiv  

Transcriptome Landscape of Cancer‐Associated Fibroblasts in Human PDAC

open access: yesAdvanced Science, EarlyView.
AP‐1 family members FOS and JUN regulate the malignant phenotype conversion of normal fibroblasts (NFs) to normal‐like cancer‐associated fibroblasts (nCAFs), while transforming growth factor‐β (TGFβ) and interferon‐γ (IFNγ) signals triggers the interconversion between classic myofibroblastic CAFs (myCAFs) and inflammatory CAFs (iCAFs), respectively ...
Mengyu Tao   +15 more
wiley   +1 more source

Evaluation of the characteristics of workers injured on the job requiring hospitalization, and employer compliance with OSHA's reporting requirement for these work‐related hospitalizations

open access: yesAmerican Journal of Industrial Medicine, Volume 66, Issue 2, Page 109-121, February 2023., 2023
Abstract Background The Occupational Safety and Health Administration (OSHA) implemented a new standard in 2014 requiring employers to report nearly all work‐related inpatient hospitalizations within 24 h of the event. We examined the characteristics of the injured workers who were reported and the compliance of Michigan employers with the regulation ...
Mary Jo Reilly   +2 more
wiley   +1 more source

Defining Name Accessibility using Scope Graphs (Extended Edition) [PDF]

open access: yesarXiv
Many programming languages allow programmers to regulate accessibility; i.e., annotating a declaration with keywords such as export and private to indicate where it can be accessed. Despite the importance of name accessibility for, e.g., compilers, editor auto-completion and tooling, and automated refactorings, few existing type systems provide a ...
arxiv  

Development of MDM2‐Targeting PROTAC for Advancing Bone Regeneration

open access: yesAdvanced Science, EarlyView.
This work presents a creative pipeline for developing MDM2‐targeting PROTACs (MDM2‐PROTACs) for application in bone regeneration. The developed PROTACs (CL144 and CL174) are validated for their degradation efficiency and osteogenic effects in human BMSCs.
Sol Jeong   +17 more
wiley   +1 more source

Teaching perspectives on the communication of difficult news of genetic conditions to medical students

open access: yesAmerican Journal of Medical Genetics Part A, Volume 191, Issue 1, Page 299-305, January 2023., 2023
Abstract Informing parents that their child has a diagnosis of Down syndrome (DS) is a common example of the delivery of unexpected or difficult news. Expectations and life planning will change, and if detected prenatally, discussions might include the option of pregnancy termination.
Ashley M. Vanasse   +8 more
wiley   +1 more source

Digital Accessibility Literacy: A Conceptual Framework for Training on Digital Accessibility [PDF]

open access: yesarXiv
Developing digital accessibility expertise is critical to breaking down barriers and ensuring digital inclusion. However, a discourse on a pedagogical culture for teaching digital literacy is still lacking. This article, therefore, takes up the current discourse on the description of literacy and uses it to develop the concept of digital accessibility ...
arxiv  

IR783‐Stabilized Nanodrugs Enhance Anticancer Immune Response by Synergizing Oxidation Therapy and Epigenetic Modulation

open access: yesAdvanced Science, EarlyView.
IR783‐stabilized nanodrugs composed of NIR dye IR783, ROS inducer β‐lapachone, and epigenetic modulator CUDC101 are designed for breast cancer immunotherapy. The nanodrugs can not only promote cancer cell apoptosis through HDAC inhibition‐enhanced oxidation therapy but also reshape the immunosuppressive microenvironment, which provides a novel strategy
Jinzhao Liu   +6 more
wiley   +1 more source

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