Results 41 to 50 of about 1,242,519 (279)

Portuguese and Spanish DMOs’ Accessibility Apps and Websites

open access: yesJournal of Theoretical and Applied Electronic Commerce Research, 2021
“Tourism for all” is based on three main aspects: accessible tourism, sustainable tourism and social tourism. Accessibility is an essential part of responsible and sustainable tourism.
Elena Fernández-Díaz   +2 more
doaj   +1 more source

UNIVERSITY WEBSITE ACCESSIBILITY FOR TOTALLY BLIND USERS

open access: yesJournal of ICT, 2017
Researchers have discovered significant faults in the accessibility of university websites, especially for visually-impaired users. To determine the requirements for totally blind users, this study conducted a comprehensive literature review and ...
Mohammed Hassouna   +2 more
doaj   +3 more sources

21. Applying Universal Instructional Design to Course Websites by Using Course Evaluations

open access: yesCollected Essays on Learning and Teaching, 2012
The authors explore their use of learner-centred teaching strategies and Universal Instructional Design (UID) on course websites. UID is based on universal design, the design of products and environments intended to be usable by all people to the ...
Irene Carter, Donald Leslie, Denise Kwan
doaj   +1 more source

United by Hope, Divided by Access: Country Mapping of COVID-19 Information Accessibility and Its Consequences on Pandemic Eradication

open access: yesFrontiers in Medicine, 2021
Many government websites and mobile content are inaccessible for people with vision, hearing, cognitive, and motor impairments. The COVID-19 pandemic highlighted these disparities when health authority website information, critical in providing resources
Amiel A. Dror   +21 more
doaj   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Accessibility, usability, and security evaluation of Hungarian government websites

open access: yesUniversal Access in the Information Society, 2020
Public sector bodies are increasingly relying on the Internet. On this channel, indispensable information is transmitted to the public and a wide range of services is already available.
Balázs Csontos, I. Heckl
semanticscholar   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Augmenting Tourism Websites With Voice Commands for Increasing Accessibility in Smart Tourism Destinations

open access: yesIEEE Access
Accessibility of tourism destination of official websites has been widely considered under the umbrella of Smart Tourism Destinations. Unfortunately, digital accessibility perceived by users is still a challenge since there are a plethora of websites ...
Cesar Gonzalez-Mora   +4 more
doaj   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

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