Results 41 to 50 of about 199,840 (302)

Assessing web content accessibility of E-commerce websites for people with disabilities [PDF]

, 2016
In recent years online shopping has grown significantly. Due to the rapid growth of technology, companies also continuing to extend the functionality and design of their Business-to-Consumer (B2C) e-business websites.
Kang, K, Sohaib, O
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

A Review of Selected E-Recruiting Websites: Disability Accessibility Considerations [PDF]

, 2002
Ten job boards1 and 31 corporate E-recruiting websites were evaluated for accessibility for people with disabilities. The examination was performed using both an automated accessibility testing software (Bobby v3.2) and an examination of a sub-sample of ...
Erickson, William
core   +1 more source

Accessibility of Tourism Websites: Attitudes and Behaviors

, 2014
While developed countries continue to shape an industry that has somehow become an integral part of the society, it only seems fair that the industry should provide equal access for every member of the society, recouping members of the market that is ...
Armadita, Filza
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

ILR Impact Brief - Community College Websites and Barriers to Access [PDF]

, 2008
[Excerpt] Community colleges, on average, serve 335 students with disabilities, although that number climbs to 5,000 at the largest college surveyed for this project.
Bruyere, Susanne M, Erickson, William, Lee, Camille G, Trerise, Sharon, VanLooy, Sara   +4 more
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Augmenting Tourism Websites With Voice Commands for Increasing Accessibility in Smart Tourism Destinations

IEEE Access
Accessibility of tourism destination of official websites has been widely considered under the umbrella of Smart Tourism Destinations. Unfortunately, digital accessibility perceived by users is still a challenge since there are a plethora of websites ...
Cesar Gonzalez-Mora, Irene Garrigos, Marco A. Celdran-Bernabeu, David Giner-Sanchez, Jose-Norberto Mazon   +4 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Portuguese and Spanish DMOs’ Accessibility Apps and Websites

Journal of Theoretical and Applied Electronic Commerce Research, 2021
“Tourism for all” is based on three main aspects: accessible tourism, sustainable tourism and social tourism. Accessibility is an essential part of responsible and sustainable tourism.
Elena Fernández-Díaz, Marisol B. Correia, Nelson de Matos   +2 more
doaj   +1 more source