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Granulomatosis with polyangiitis (GPA or Wegener's granulomatosis) is a rare systemic autoimmune disease of unknown etiology characterized by granulomatous inflammation, tissue necrosis, and vasculitis of small to medium-sized vessels.
A. Ulzhitaeva +5 more
doaj +1 more source
ANCA-associated vasculitis – Should we change the standard of care? [PDF]
Collaborative clinical trials over the last 25 years have revolutionised the care of patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. This has led to production of management recommendations and standards of care.
Bligny +45 more
core +1 more source
Bilateral Facial Paralysis and Otitis Media as the First Presentations of Wegener’s Granulomatosis: A Case Report [PDF]
Introduction: Cranial nerve palsy in Wegener’s granulomatosis is a curious incident, particularly if it occurs without kidney or lung involvement. In a review of medical articles, only 1 case of Wegener’s granulomatosis with bilateral facial nerve palsy ...
Seyed Mohammad Javad Hosseini +3 more
doaj +1 more source
Wegener's Granulomatosis: Strawberry Gums of the Oral Cavity
Wegener's Granulomatosis is a rare and potentially life-threatening vasculitic disease of unknown origin. The diagnosis of Wegener's Granulomatosis is made on the basis of clinical presentation, positivity for serum c-ANCA and histologic examination of ...
Hoe Kit Chee MDS (Periodontology), MRD RCSEd
doaj +1 more source
Autoimmune inflammatory disorders, systemic corticosteroids and pneumocystis pneumonia: A strategy for prevention [PDF]
Background Pneumocystis pneumonia (PCP) is an increasing problem amongst patients on immunosuppression with autoimmune inflammatory disorders (AID). The disease presents acutely and its diagnosis requires bronchoalveolar lavage in most cases.
Evin Sowden +44 more
core +2 more sources
Abstract The clinical and radiographic features of Wegener's granulomatosis are outlined. A unique case is reported where the only radiographic finding in the lungs was expansile uniform consolidation of one lobe.
R, Aach, J, Kissane
+7 more sources
CpG oligodeoxynucleotide stimulates production of anti-neutrophil cytoplasmic antibodies in ANCA associated vasculitis [PDF]
Background Wegener's Granulomatosis and Microscopic Polyangiitis are life-threatening systemic necrotizing vasculitides of unknown aetiology. The appearance of circulating antibodies to neutrophil cytoplasmic antigens (ANCA) is strongly associated with ...
Plinio R Hurtado +8 more
core +2 more sources
"Wegener’s granulomatosis in a patient with Rheumatoid arthritis " [PDF]
Wegener’s Granulomatosis is a necrotizing granulomatous vasculitis involving small and medium sized vessels. The syndrome is classically defined as having involvement of kidney, lungs and upper respiratory tract (i.e. sinuses).
"Ahmadi Nejad Z +3 more
doaj +1 more source
On the Wegener granulomatosis associated region on chromosome 6p21.3 [PDF]
Background Wegener granulomatosis (WG) belongs to the heterogeneous group of systemic vasculitides. The multifactorial pathophysiology of WG is supposedly caused by yet unknown environmental influence(s) on the basis of genetic predisposition.
Paweł Szyld +45 more
core +2 more sources
Esophageal Involvement in Wegener’s Granulomatosis: A Case Report and Review of the Literature
Wegener’s granulomatosis is characterized by a granulomatous arteritis involving the upper and lower respiratory tracts, progressive glomerulonephritis and systemic symptoms attributable to small vessel vasculitis.
Glen A Fallows +3 more
doaj +1 more source

