A Response to: Letter to the Editor Regarding "Cost-Effectiveness of Elranatamab Versus Current Therapies for the Management of Patients with Triple-Class Exposed, Relapsed and Refractory Multiple Myeloma, Including Other Bispecific and Physician's Choice of Treatment in Spain". [PDF]
Lozano V +6 more
europepmc +1 more source
GelMA/DMAEMA hybrid hydrogels for release of ibuprofen. ABSTRACT In this study, biocompatible hydrogels intended for topical delivery of ibuprofen were synthesized from gelatin methacryloyl (GelMA) and 2‐(dimethylamino)ethyl methacrylate (DMAEMA) by varying their proportions. The impact of different GelMA and DMAEMA ratios was comprehensively evaluated
Guilherme Frey Schutz +7 more
wiley +1 more source
Testing for Sufficient Follow‐Up in Survival Data With a Cure Fraction
ABSTRACT In order to estimate the proportion of “immune” or “cured” subjects who will never experience failure, a sufficiently long follow‐up period is required. Several statistical tests have been proposed in the literature for assessing the assumption of sufficient follow‐up, meaning that the study duration is longer than the support of the survival ...
Tsz Pang Yuen, Eni Musta
wiley +1 more source
Abemaciclib is an oral anticancer drug indicated for treatment of HR+ HER2‐ breast cancer. Dose modifications due to side effects are frequent, thus drug exposures change over time as a result of altering the dose or temporarily withholding abemaciclib treatment.
Emmanuel Chigutsa +2 more
wiley +1 more source
Fatigue Analysis and Numerical Simulation of Loess Reinforced with Permeable Polyurethane Polymer Grouting. [PDF]
Yue L +6 more
europepmc +1 more source
ABSTRACT The expanding demand for platinum group elements (PGEs) in industrial and medical applications has led to their increasing accumulation in aquatic sediments. However, their ecological impacts remain poorly understood, particularly for sediment‐dwelling invertebrates. This study assessed the toxicity of platinum (Pt) and palladium (Pd) across a
Alice Carle +3 more
wiley +1 more source
Multivariate Tests for Comparing Lifetimes of Parallel Systems
ABSTRACT Life testing of engineering systems with dependent components requires robust multivariate methods. Parametric approaches depend on restrictive assumptions, limiting their use in complex or unknown lifetime distribution settings. This study evaluates nonparametric methods for comparing parallel system lifetimes under minimal sample ...
Niladri Chakraborty +2 more
wiley +1 more source
Predicting extreme thermal degradation of ascorbic acid (Vitamin C) using Bayesian-Inverse Weibull models: Applications in stability analysis and process optimization. [PDF]
Azeem R, Aslam M, Mehmood T, Al-Essa LA.
europepmc +1 more source
Optimal Accelerated Life Testing Design Under Constrained Resources Using Double Deep Q‐Learning
ABSTRACT Accelerated life tests (ALTs) are essential tools for estimating product reliability under high‐stress conditions, allowing failure data to be collected in reduced timeframes. However, planning effective ALT configurations is a complex task that requires selecting stress levels, test durations, and unit allocations while accounting for limited
Allan Jonathan da Silva +3 more
wiley +1 more source
Fitting high-dimensional mixture cure models using the hdcuremodelsR package. [PDF]
Archer KJ, Fu H.
europepmc +1 more source

