Results 111 to 120 of about 68,425 (202)

Association between metabolic syndrome, macular structures and retinal vascular calibres in the Northern Finland Birth Cohort Eye Study

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose We aimed to evaluate the association of metabolic syndrome (MetS) with macular thickness and retinal vascular calibres in the population‐based cohort (Northern Finland Birth Cohort). Methods The population of 2242 individuals was divided into MetS (n = 344) and control groups (n = 1898).
Jenni M. Huru   +4 more
wiley   +1 more source

Dynamics of Body Composition and Metabolic Risk in Adolescents With Obesity Under GLP‐1 Receptor Agonist Therapy

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim To explore changes in body composition in adolescents with obesity treated with glucagon‐like peptide‐1 receptor agonist (GLP‐1 RA) and their association with metabolic syndrome (MetS) components. Methods This real‐world retrospective study included adolescents (12–18 years) with obesity who received multidisciplinary lifestyle‐based ...
Adar Lopez   +11 more
wiley   +1 more source

Cardiovascular Health Was Moderate in Austrian Adolescents and Showed an Inverse Relationship With High‐Sensitivity C‐Reactive Protein Levels

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim This Prospective, Community‐Based Cohort Study Investigated Cardiovascular Health and Its Association With Low‐Grade Inflammation in Adolescents. Methods Data were collected by specially trained medical staff from 1379 Austrian adolescents aged 14–19 years from 3 February 2021 to 28 February 2023.
Katharina Mueller   +6 more
wiley   +1 more source

Metabolic Risk Factors Are Associated With Weight Status Change Over Four Years in Children Aged 4–6 Years With Obesity

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim It is unclear how early childhood obesity treatment affects metabolic risk. This study assessed long‐term metabolic health in children with obesity aged 4–6 years and examined associations with weight status. Methods This prospective cohort study pooled data from the Sweden‐based More and Less randomized controlled trial, which compared a ...
Markus Brissman   +6 more
wiley   +1 more source

Validation of the Milan Score Using Prolonged Wireless PH Monitoring

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
The Milan Score, a high‐resolution manometry‐derived tool, predicts pathological GERD on 96‐h wireless pH monitoring with high specificity and positive predictive value, maintaining robust discriminative performance across both typical and atypical symptom profiles and outperforming single HRM parameters as a standalone manometric parameter.
Stefano Siboni   +8 more
wiley   +1 more source

Risk Prediction of Early‐Onset Hepatocellular Carcinoma: Derivation and Validation in a Nationwide Young Adult Cohort

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In 1,756,593 young adults, a generalized boosted survival model predicted incident HCC with strong discrimination (1‐year AUROC 0.945; 5‐year 0.825). The 1‐year horizon uniquely targets an imaging‐silent, pre‐diagnosis window, showing routine clinical signals can flag otherwise undetectable risk.
Seogsong Jeong   +7 more
wiley   +1 more source

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