Results 41 to 50 of about 72,685 (204)

Weight-adjusted-waist index: an innovative indicator of breast cancer hazard

BMC Women's Health
Background Central obesity and breast cancer (BC) have been identified as relevant by empirical research. The weight-adjusted-waist index (WWI) is a novel methodology for quantifying central obesity.
Xinyi Huang, Hengzheng Cheng, Laifu Deng, Shuting Wang, Jiaxiu Li, An Qin, Chunqiang Chu, Wenyi Du, Xiao Liu   +8 more
doaj   +1 more source

Sports Activity Recognition Using Textile‐Based Sensor Fusion and Complex‐Valued Residual Convolutional Neural Networks

Advanced Intelligent Systems, EarlyView.
Motion artifacts in electrocardiographic signals, conventionally dismissed as noise, are shown to encode discriminative activity information. A smart t‐shirt fusing textile strain sensors with textile ECG electrodes, processed through a complex‐valued residual network, recognizes 12 sport activities.
Nada Al‐azzawi, Munire Sibel Cetin, Asli Tuncay Atalay, Ozgur Atalay, Gökhan Ince   +4 more
wiley   +1 more source

An Active Knee–Ankle–Foot Orthosis With Torque‐Dense, Low‐Impedance Knee Actuation

Advanced Intelligent Systems, EarlyView.
This article presents the simulation, design, and clinical validation of a robotic active KAFO with torque‐sensitive actuation. By passively and continuously adapting the transmission ratio in response to the knee torque, the torque‐sensitive actuator overcomes the tradeoff between torque, weight, and impedance observed in conventional robot actuators,
Brendon Ortolano, Kai Pruyn, Rosemarie Murray, Lukas Gabert, Tommaso Lenzi   +4 more
wiley   +1 more source

Transcriptomic Profiling in Skeletal Muscle Identifies Associations With Knee Osteoarthritis: The Study of Muscle, Mobility and Aging

Arthritis &Rheumatology, EarlyView.
Objective The association between skeletal muscle gene expression and knee osteoarthritis (OA) was examined among older adult participants of the Study of Muscle, Mobility and Aging (SOMMA). Methods Inclusion criteria included knee radiographs and bulk RNA sequencing in vastus lateralis muscle, resulting in 523 participants (56% female).
Daniel S. Evans, Tyler A. Mansfield, Gina M. Many, Tyler J. Sagendorf, Samaneh Farsijani, Bret H. Goodpaster, Lauren M. Sparks, Nancy E. Lane   +7 more
wiley   +1 more source

Nonlinear association between weight-adjusted-waist index and colorectal cancer in adults

Critical Public Health
Colorectal cancer (CRC) remains a major global health burden, with increasing incidence among younger adults. Obesity and visceral fat accumulation are known contributors to CRC risk, yet conventional anthropometric indices have limitations in accurately
Pinggang Ding, Zhengjiu Cui, Xin Liu, Lu Wang, Zhimin Fan   +4 more
doaj   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Association between weight-adjusted-waist index and chronic kidney disease: a cross-sectional study

BMC Nephrology, 2023
Aims We aimed to investigate the potential association between weight-adjusted-waist index (WWI) and chronic kidney disease (CKD). Design and methods This research examined data collected from the National Health and Nutrition Examination Survey (NHANES)
Xiaowan Li, Lanyu Wang, Hongyi Zhou, Hongyang Xu   +3 more
doaj   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

British Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza, Andrej Belancic, Jens Jordan, Alberto Esteban, Anna Oliveras, Ryan McNally, Panagiota Anyfanti, Jorie Versmissen, María S. Fernández‐Alfonso, Vasilios Kotsis, Thomas Weber, Alexandre Persu, Reinhold Kreutz   +12 more
wiley   +1 more source

Residual Shunt at 6 Months Follow‐up After Percutaneous Patent Foramen Ovale Closure in CAHAL: A Comparison of Occlutech and Amplatzer

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Residual shunt is a known complication in percutaneous patent foramen ovale (PFO) closure, and moderate to large residual shunt has been associated with an increased risk of recurrent stroke. Device‐related factors, such as device size, have been associated with residual shunt, but comparative data per device type are scarce.
Jelle D. Nieuwendijk, Abdelhak el Bouziani, Lars S. Witte, Danielle Robbers‐Visser, Berto J. Bouma, Bart Straver, Ibtihal al Amri, Jonathan M. Coutinho, Ronak Delewi, Robbert J. de Winter, Marcel A. M. Beijk, Frank van der Kley, Maik J. Grundeken   +12 more
wiley   +1 more source