Results 151 to 160 of about 7,387,955 (262)
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Portrait of Pro Hart, 2003 [picture] /
, 2003 Title from inscription.; Inscriptions: "Greg Weight 2003"--In pencil lower right on verso; "Pro Hart 2003"--In pencil lower left on verso; Embossed stamp with photographer's initials lower right.; Also available in an electronic version via the Internet ...
Weight, Greg, 1946-
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Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Portrait of Stephen Killick, 2004 [picture] /
, 2004 Title from inscription.; Inscriptions: "Greg Weight 2004"--In pencil lower right on verso; "Stephen Killick 2004"--In pencil lower left on verso; Embossed stamp with photographer's initials lower right.; Also available in an electronic version via the ...
Weight, Greg, 1946-
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FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
John Olsen in bathtub, Rydal, 1996 [picture] /
, 1996 Title from caption on item.; Condition: good.; Two prints from the same negative.; Inscriptions: Larger print: "John Olsen 1996"-- in pencil on reverse l. l. corner. "Photograph by Greg Weight c1996"--in pencil on reverse l.r. corner.
Weight, Greg, 1946-
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Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Peter Wright, Hill End, 1999 [picture] /
, 1999 Title from caption; Inscriptions: Larger print: "Peter Wright. Hill End 1999" - in pencil on reverse l.l. corner. "Photograph Greg Weight 1999" - in pencil on reverse l.r. corner.
Weight, Greg, 1946-
core