Results 71 to 80 of about 2,158,968 (267)
Weighted-Type Wishart Distributions with Application
In this paper, we consider a general framework for constructing new valid densities regarding a random matrix variate. However, we focus specifically on the Wishart distribution.
M. Arashi , A. Bekker, Janet van Niekerk
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
On a Reverse Half-Discrete Hardy-Hilbert’s Inequality with Parameters
By means of the weight functions, the idea of introduced parameters, and the Euler-Maclaurin summation formula, a reverse half-discrete Hardy-Hilbert’s inequality and the reverse equivalent forms are given.
Bicheng Yang, Shanhe Wu, Aizhen Wang
doaj +1 more source
A Weight Sequence Distance Function [PDF]
In this paper, a family of weighted neighborhood sequence distance functions defined on the square grid is presented. With this distance function, the allowed weight between any two adjacent pixels along a path is given by a weight sequence. We build on our previous results, where only two or three unique weights are considered, and present a framework
Benedek Nagy +2 more
openaire +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Bilateral generating functions for a new class of generalized Legendre polynominals
Recently Chatterjea (1) has proved a theorem to deduce a bilateral generating function for the Ultraspherical polynomials. In the present paper an attempt has been made to give a general version of Chatterjea's theorem.
A. N. Srivastava +2 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Multipliers on some weighted Lp-spaces
Let G be a locally compact abelian group with Haar measure dx, and let ω be a symmetric Beurling weight function on G (Reiter, 1968).
S. Öztop
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

