Results 121 to 130 of about 711,326 (263)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

The effect of gestational weight gain on the infant gut microbiome- a systematic review of the literature. [PDF]

open access: yesFront Cell Infect Microbiol
Xixi NA   +9 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Uso del probiótico Sorbifauna en el crecimiento de crías ovinas estabuladas

open access: yesPastos y Forrajes
Con el objetivo de evaluar el efecto que ejerce la inclusión del probiótico Sorbifauna en el crecimiento de crías ovinas estabuladas, se realizó un estudio en condiciones de producción.
Y López, J Arece, F Ojeda, M Molina
doaj  

Adequacy of gestational weight gain according to the brazilian charts: a comparison with the Institute of Medicine recommendations. [PDF]

open access: yesRev Bras Ginecol Obstet
de Moraes MC   +7 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Wheat Flour Intake Promotes Weight Gain and Metabolic Changes in Mice. [PDF]

open access: yesMol Nutr Food Res
Matsumura S   +14 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Recommendations for energy intake and weight gain for pregnant women with obesity. [PDF]

open access: yesChin Med J (Engl)
Juan J   +9 more
europepmc   +1 more source

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