Results 61 to 70 of about 719,182 (313)
Preventing Excessive Weight Gain [PDF]
,Brownetal.(1)providemore evidence that the obesity epidemic has arisen fromgradual weight gain in the population produced by verysmall degrees of energy imbalance. The authors followedover 8000 middle-aged women in Australia for more than 5years, from 1996 to 2001. They found that the womengained an average of 0.5 kg/yr.
openaire +2 more sources
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Coping with Stress in Complicated Pregnancy and Gestational Weight Gain [PDF]
Agnieszka Rolińska +2 more
openalex +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
IMPLIKASI PIJAT BAYI TERHADAP PENINGKATAN BERAT BADAN PADA BAYI USIA 6-8 BULAN
Infant massage has been practiced almost all over the world since ancient times, including Indonesia. Baby massage art is taught hereditary although it is not known clearly how massage and touch can have a positive effect on the human body.
Prodalima Sinulingga, Delfriana Ayu A
doaj +1 more source
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Zachary M Ferraro,1 Kaitlin S Boehm,1 Laura M Gaudet,2,3 Kristi B Adamo1,4,5 1Healthy Active Living and Obesity Research Group, Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada; 2Horizon Health Network, Saint John ...
Ferraro ZM +3 more
doaj
Purebred and crossbred calves (n = 3,871) were selected that were born in the sub-region of the Pantanal of Aquidauana (Brazil), derived from Nellore, Brangus, Wagyu, and ½ Brangus + ½ Nellore cows, which were artificially inseminated by bulls of the ...
Fabio Rafael Leão Fialho +5 more
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