Results 61 to 70 of about 758,503 (311)
Gestational weight gain and birth weight of newborn
Wen-Hsun Chang +2 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Selenium improves weight gain of beef calves
Although the effects of weight loss from selenium-deficient cattle is less dramatic than death caused by white muscle disease (also resulting from selenium deficiency), the economic loss can be severe. Treatments with injections of selenium have produced
W Johnson, B Norman, J Dunbar
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Introduction: Birth weight is one of the main determinators for somatic and mental growth in infants and it is an important symptom of intrauterine growth. Thus recognition of factors that affects the low birth weight and elimination of them is
masoumeh delaram, nasrin akbari
doaj
Factors Associated with Interdialytic Weight Gain and Its Percentage: Are 2 Metrics Interchangeable?
Background: Interdialytic weight gain (IDWG) is a key indicator of fluid management in hemodialysis patients. Greater IDWG reflects nonadherence to fluid restriction, excessive salt intake, and has been associated with reduced quality of life, increased
Duc Manh Nguyen
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
IntroductionExcessive body weight was associated with changes in individual microbiota. However, limited research on the impact of excessive gestational weight gain (GWG) revealed that microbiota patterns related to GWG differed from those linked to ...
Katarzyna Kosinska-Kaczynska +13 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

