Results 181 to 190 of about 632,681 (338)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Optimal error estimates of the diffuse domain method for second order parabolic equations. [PDF]

BIT Numer Math
Hao W, Ju L, Xu Y.
europepmc   +1 more source

Approximation Numbers of Composition Operators on Weighted Hardy Spaces [PDF]

, 2015
Ajay K‎. ‎Sharma, Ambika Bhat
openalex   +1 more source

Superpixel Weighted Low-rank and Sparse Approximation for Hyperspectral Unmixing

, 2022
Taner İnce, Tuğcan Dündar, Seydi Kaçmaz, Hasarı Karcı   +3 more
openalex   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Compact and Interpretable Neural Networks Using Lehmer Activation Units. [PDF]

Entropy (Basel)
Ataei M, Forouzi S, Wang X.
europepmc   +1 more source

Approximations for node-weighted Steiner tree in unit disk graphs

, 2010
X. P. Xu, Yue Wang, Hongwei Du, P.-J. Wan, Feng Zou, Xiaojun Li, Weili Wu   +6 more
openalex   +2 more sources

A weighted setting for the numerical approximation of the Poisson\n problem with singular sources [PDF]

, 2018
Irene Drelichman, Ricardo G. Durán, Ignacio Aymerich Ojea   +2 more
openalex   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Multi-modal Monte Carlo MRI simulator of tissue microstructure. [PDF]

Imaging Neurosci (Camb)
Cottaar M, Zheng Z, Miller K, Tendler BC, Jbabdi S.   +4 more
europepmc   +1 more source