Results 81 to 90 of about 530,949 (219)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Vacation request for Sophia Good Blanket (Drunkard)

open access: yes, 1919
Vacation request for Sophia Good Blanket (Drunkard) from her ...
Good Blanket, Irving (Drunkard)
core  

Controls on Carbon Cycling in Upland Blanket Peat Soils [PDF]

open access: yes, 2012
Peatlands are a globally important, terrestrial store of carbon and the UK is recognised as an internationally significant holder of peatlands. Of all the kinds of peatland found in the UK, blanket bogs are dominant, representing 87% of the UK’s peatland
DIXON, SIMON,DAVID
core  

blanket with beaded strip

open access: yes
See notes2.49 mBlue wool blanket with beaded blanket strip down center, two sides bound in red braid. Blanket is made by two pieces sewn together. Blanket strip is 54.0 long, with chalk white background with 5 designs spaced at intervals in green, blue ...
Omaha
core   +1 more source

Identifying the driving mechanisms of ecosystem health in a typical ecologically fragile region: A study based on the XGBoost–SHAP model

open access: yesEcological Indicators
Accurately assessing ecosystem health is essential for effective environmental management, particularly in ecologically fragile regions like the Loess Plateau.
Di Yu   +6 more
doaj   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Accelerating the engineering design of breeder blankets with parametric optimisation and sequential learning

open access: yesFrontiers in Nuclear Engineering
The competing requirements of fusion breeder blankets and the high dimensionality of their design space necessitate a systematic treatment to map the variations in performance against given objective metrics and to understand the operational envelope. In
Luke Humphrey   +4 more
doaj   +1 more source

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