Results 41 to 50 of about 499,844 (203)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Effectiveness of weighted blankets as an intervention for sleep problems in children with autism [PDF]
, 2014 Sleep problems are common in children with ASD. Despite this, evidence for interventions, particularly alternative approaches such as weighted blankets is limited. Aims.
Charleson, Jane Louise
core +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Weighted blankets for insomnia in affective disorder and ADHD – a clinical follow up study
, 2018 Introduction: Weighted blankets are used for the treatment of insomnia in patients with affective disorders and ADHD, despite the lack of scientific support. This study aimed to evaluate the clinical use of weighted blankets for insomnia in patients with
Mats Adler, Bodil Ekholm
core +4 more sources
Occupational Therapy Interventions for Acute Psychiatric Inpatients: A Scoping Review [PDF]
Journal of Rehabilitation Sciences and ResearchBackground: In recent decades, policy changes in many countries have significantly affected the treatment of people with mental illness (MI), particularly in reducing the length of hospitalization in acute psychiatric departments. Occupational therapists,
Hajar Sabour Eghbali MostafaKhan +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Effects of Weighted Blankets on College Students’ Anxiety [PDF]
, 2019 Background: Many mental health disorders, including anxiety, are identified during young adulthood when students are beginning college. Therapies such as weighted blankets may provide anxiety relief, but information about the use of weighted blankets for
Clapp, Amy
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source