Results 51 to 60 of about 63,505 (342)

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Norms of Composition Operators from Weighted Harmonic Bloch Spaces into Weighted Harmonic Zygmund Spaces

Journal of Function Spaces
This article examines the norms of composition operators from the weighted harmonic Bloch space BHλ ...
Munirah Aljuaid, M. A. Bakhit
doaj   +1 more source

Weighted differentiation composition operators from the logarithmic Bloch space to the weighted-type space

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2016
The boundedness of the weighted differentiation composition opera- tor from the logarithmic Bloch space to the weighted-type space is characterized in terms of the sequence (zn)n∈N0.
Li Songxiao, Stević Stevo
doaj   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Non-Weakly Supercyclic Weighted Composition Operators

Abstract and Applied Analysis, 2010
We give sufficient conditions under which a weighted composition operator on a Hilbert space of analytic functions is not weakly supercyclic. Also, we give some necessary and sufficient conditions for hypercyclicity and supercyclicity of weighted ...
Z. Kamali, K. Hedayatian, B. Khani Robati   +2 more
doaj   +1 more source

Compact generalized weighted composition operators on the Bergman space [PDF]

Opuscula Mathematica, 2017
We characterize the compactness of the generalized weighted composition operators acting on the Bergman space.
Qinghua Hu, Xiangling Zhu
doaj   +1 more source

Composition Operators From Harmonic Lipschitz Space Into Weighted Harmonic Zygmund Space

International Journal of Analysis and Applications, 2023
The paper investigate a necessary and sufficient condition for the composition operator from harmonic Lipschitz spaces LipHα ...
M. A. Bakhit, N. M. Dahshan, Ranya Tahier, Omniat O. Y. Karrar, Mehreen S. Khan, M. A. Orsud   +5 more
doaj   +1 more source

Weighted Composition Operators on BMOA [PDF]

Computational Methods and Function Theory, 2008
Let ψ and φ be analytic functions on the unit disk D such that φ(D) ⊂ D. We characterize the boundedness and compactness of the weighted composition operators f ↦ ψ · (f oφ) on BMOA, the space of analytic functions on D that have bounded mean oscillation on ∂D, and its subspace VMOA.
openaire   +2 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Binormal and complex symmetric weighted composition operators on the Fock Space over $\mathbb{C}$

Математичні Студії, 2023
In this paper, we give simple characterization of binormal weighted composition operators $C_{\psi, \phi}$ on the Fock space over $\mathbb{C}$ where weight function is of the form $\psi(\zeta) = e^{\langle \zeta, c \rangle}$ for some $c \in \mathbb{C ...
C. Santhoshkumar
doaj   +1 more source