Results 31 to 40 of about 5,409 (243)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Compact Weighted Composition Operators and Multiplication Operators between Hardy Spaces

open access: yesAbstract and Applied Analysis, 2008
We estimate the essential norm of a compact weighted composition operator 𝑢𝐶𝜑 acting between different Hardy spaces of the unit ball in ℂ𝑁. Also we will discuss a compact multiplication operator between Hardy spaces.
Sei-Ichiro Ueki, Luo Luo
doaj   +1 more source

Weighted Composition Operators on Hardy Spaces

open access: yesJournal of Mathematical Analysis and Applications, 2001
This paper studies operators of the form \(f\mapsto (f\circ\varphi)\psi\) acting on Hardy spaces \(H^p\) of the unit disk \(D\), where \(\psi\) is analytic in \(D\) and \(\varphi\) is an analytic self-map of \(D\). Problems studied include the boundedness, compactness, weak compactness, and complete continuity of such operators.
Contreras, Manuel D   +1 more
openaire   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Weighted Composition Operators Between Different Fock Spaces [PDF]

open access: yesPotential Analysis, 2018
We study weighted composition operators acting between Fock spaces. The following results are obtained: (1) Criteria for the boundedness and compactness; (2) Characterizations of compact differences and essential norm; (3) Complete descriptions of path connected components and isolated points of the space of composition operators and the space of ...
Tien, Pham Trong, Khoi, Le Hai
openaire   +4 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Weighted Composition Operators on the Zygmund Space

open access: yesAbstract and Applied Analysis, 2012
We characterize the boundedness and compactness of the weighted composition operator on the Zygmund space Z={f∈H(D):sup⁡z∈D(1-|z|2)|f″(z)|
Shanli Ye, Qingxiao Hu
doaj   +1 more source

Weighted Composition Operators on Quasi-Banach Weighted Sequence Spaces

open access: yesSiberian Mathematical Journal, 2023
В работе рассматриваются основные топологические свойства операторов весовой композиции на весовых пространствах последовательностей $l^p(\text{w})$, $0<p<\infty,$ где $\text{w}$ - весовая последовательность положительных чисел: ограниченность, компактность, компактность разностей операторов, формулы для их существенных норм, а также описание тех
A. V. Abanin, R. S. Mannanikov
openaire   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Differences of Weighted Composition Operators on Hα∞(BN)∗

open access: yesJournal of Inequalities and Applications, 2009
We study the boundedness and compactness of differences of weighted composition operators on weighted Banach spaces in the unit ball of CN.
Jineng Dai, Caiheng Ouyang
doaj   +1 more source

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