Results 101 to 110 of about 35,359 (261)

Managing large distributed dynamic graphs for smart city network applications

Applied Network Science, 2019
Smart cities and traffic applications can be modelled by dynamic graphs for which vertices or edges can be added, removed or change their properties. In the smart city or traffic monitoring problem, we wish to detect if a city dynamic graph maintains a ...
Nadav Voloch, Noa Voloch - Bloch, Yair Zadok   +2 more
doaj   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

An Entropy-Based Adaptive Hybrid Particle Swarm Optimization for Disassembly Line Balancing Problems

Entropy, 2017
In order to improve the product disassembly efficiency, the disassembly line balancing problem (DLBP) is transformed into a problem of searching for the optimum path in the directed and weighted graph by constructing the disassembly hierarchy information
Shanli Xiao, Yujia Wang, Hui Yu, Shankun Nie   +3 more
doaj   +1 more source

Weighted Directed Graph-Based Authorization Delegation Model

Journal of Networks, 2013
In this paper, a new authorization delegation model is proposed, which is based on weighted directed graph to present the trust relationship between the entities and the existing issues, such as the evaluation of the trust and the presentation of the trust among the entities are addressed in simple and visual way.
openaire   +1 more source

Weighted Consensus Problem for Multiagent Systems with Edge‐ and Node‐Weighted Directed Graphs

Complexity, 2019
In this paper, the concept of consensus is generalized to weighted consensus, by which the conventional consensus, the bipartite consensus, and the cluster consensus problems can be unified in the proposed weighted consensus frame. The dynamics of agents are modeled by the general linear time‐invariant systems.
Lixin Gao 0004, Hui Fang, Wenhai Chen, He Cao   +3 more
openaire   +2 more sources

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Evaluating a Pragmatic Strength Alternative for Frailty Measurement and Assessing Its Predictive Capacity Against Established Frailty Instruments in Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective Frailty occurs prematurely in rheumatoid arthritis (RA) and is associated with poor health outcomes. We compared the performance of four frailty instruments, including a pragmatic alternative measure using chair sit‐to‐stand (STS), and evaluated their abilities to predict poor health outcomes.
Kylie E. Riggles, Hannah F. Brubeck, Adrienne D. Tanus, Courtney N. Loecker, Punyasha Roul, Bryant R. England, Elizabeth R. Wahl, James S. Andrews, Namrata Singh, Joshua F. Baker, Patricia P. Katz, Dolores M. Shoback, Jose M. Garcia, Ariela R. Orkaby, Katherine D. Wysham   +14 more
wiley   +1 more source

Strongly connected dominating set construction algorithm balancing time delay and energy consumption

Tongxin xuebao, 2012
To the asymmetry of link in wireless sensor networks,a problem about the strongly connected dominating tree with bounded transmission delay (SDTT) was put forward.The distributed strongly connected dominating tree (SCDT) algorithm was also proposed to ...
Yan-jing SUN, Jian-sheng QIAN, Shan-shan MA, Peng REN   +3 more
doaj   +2 more sources