Results 61 to 70 of about 903,926 (277)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Numerical solutions of a class of second order boundary value problems on using Bernoulli Polynomials

open access: yes, 2013
The aim of this paper is to find the numerical solutions of the second order linear and nonlinear differential equations with Dirichlet, Neumann and Robin boundary conditions.
Islam, Md. Shafiqul, Shirin, Afroza
core   +1 more source

Quark and Gluon Tagging at the LHC [PDF]

open access: yes, 2011
Being able to distinguish light-quark jets from gluon jets on an event-by-event basis could significantly enhance the reach for many new physics searches at the Large Hadron Collider.
G. Dissertori   +2 more
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Component Selection in the Additive Regression Model [PDF]

open access: yes, 2010
Similar to variable selection in the linear regression model, selecting significant components in the popular additive regression model is of great interest.
Cui, Xia   +3 more
core  

An Evaluation of Design-based Properties of Different Composite Estimators

open access: yes, 2020
For the last several decades, the US Census Bureau has been using the AK composite estimation method to produce statistics on employment from the Current Population Survey (CPS) data.
Bonnéry, Daniel   +2 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Gaussian mixture gain priors for regularized nonnegative matrix factorization in single-channel source separation [PDF]

open access: yes, 2012
We propose a new method to incorporate statistical priors on the solution of the nonnegative matrix factorization (NMF) for single-channel source separation (SCSS) applications.
Erdogan, Hakan   +2 more
core  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

A Hybrid Neuro-Fuzzy Approach for Heterogeneous Patch Encoding in ViTs Using Contrastive Embeddings and Deep Knowledge Dispersion

open access: yesIEEE Access, 2023
Vision Transformers (ViT) are commonly utilized in image recognition and related applications. It delivers impressive results when it is pre-trained using massive volumes of data and then employed in mid-sized or small-scale image recognition evaluations
Syed Muhammad Ahmed Hassan Shah   +5 more
doaj   +1 more source

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