Results 61 to 70 of about 204,251 (257)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Identification of a weighted combination of multivariable state space systems from input and output data [PDF]

, 2001
Discusses a method for the determination of a weighted combination of local linear state-space systems from input and output data. The method is iterative and each iteration consists of two steps.
Verdult, V., V. Verdult, M. Verhaegen, Verhaegen, M.H.G.   +3 more
core   +1 more source

Node-Max-Cut and the Complexity of Equilibrium in Linear Weighted Congestion Games [PDF]

, 2020
In this work, we seek a more refined understanding of the complexity of local optimum computation for Max-Cut and pure Nash equilibrium (PNE) computation for congestion games with weighted players and linear latency functions.
Skoulakis, Stratis, Fotakis, Dimitris, Mouzakis, Nikos, Patsilinakos, Panagiotis, Lianeas, Thanasis, Kandiros, Vardis   +5 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Landslide susceptibility zonation mapping using geospatial technologies and multi criteria evaluation techniques in the upper Didessa sub-basin, Southwest Ethiopia

Geology, Ecology, and Landscapes
Landslides have a profound impact on landscape geology, resulting in extensive devastation and loss of human lives. Mapping landslide susceptibility is crucial for effective land use planning in mountainous country like Ethiopia. This study was conducted
Redwan Sultan Mohammednur, Kiros Tsegay Deribew, Mitiku Badasa Moisa, Dessalegn Obsi Gemeda   +3 more
doaj   +1 more source

An approach to demarcate groundwater recharge potential zone using geospatial technology

Applied Water Science, 2020
With the increasing demands for water due to growing population, urban expansion, agricultural development and groundwater resources are gaining much attention, particularly in Gopiballavpur block, Paschim Medinipur district (West Bengal, India). Present
Gouri Sankar Bhunia
doaj   +1 more source

Local Statistical Modeling via Cluster-Weighted Approach with Elliptical Distributions [PDF]

Cluster Weighted Modeling (CWM) is a mixture approach regarding the modelisation of the joint probability of data coming from a heterogeneous population.
Giorgio Vittadini, Simona Caterina Minotti, Salvatore Ingrassia   +2 more
core  

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Biased competition in semantic representation during natural visual search

NeuroImage, 2020
Humans divide their attention among multiple visual targets in daily life, and visual search can get more difficult as the number of targets increases. The biased competition hypothesis (BC) has been put forth as an explanation for this phenomenon.
Mohammad Shahdloo, Emin Çelik, Tolga Çukur   +2 more
doaj   +1 more source