Results 41 to 50 of about 570,334 (284)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

QoE in Pull Based P2P-TV Systems: Overlay Topology Design Tradeoff [PDF]

open access: yes, 2010
—This paper presents a systematic performance anal-ysis of pull P2P video streaming systems for live applications, providing guidelines for the design of the overlay topology and the chunk scheduling algorithm. The contribution of the paper is threefold:
Traverso, Stefano   +10 more
core   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Determination of Groundwater Resources Potential in Fractured and Karstic Formations of West Azerbaijan Province [PDF]

open access: yesمجله آب و خاک
Introduction Groundwater is an important resource for domestic, agricultural, and industrial purposes (Andualem and Demeke, 2019). However, the growing population and advanced irrigation technologies have significantly led to increased groundwater ...
A. Vaezihir, M. Khalkhali, M. Tabarmayeh
doaj   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou   +16 more
wiley   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

Um overlay de roteamento tolerante a intrusões [PDF]

open access: yes, 2006
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Tecnológico. Programa de Pós-Graduação em Engenharia ElétricaÀ medida em que pessoas e organizações se tornam cada vez mais dependentes de aplicações ligadas em rede, a disponibilidade ...
Obelheiro, Rafael Rodrigues
core  

Distributed Overlay Anycast Tables using Space Filling Curves [PDF]

open access: yes, 2009
In this paper we present the Distributed Overlay Anycast Table, a structured overlay that implements application-layer anycast, allowing the discovery of the closest host that is a member of a given group.
Latif, L   +13 more
core   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

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