Results 61 to 70 of about 329,801 (266)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Journal of Inequalities and Applications, 2011 This paper characterizes the boundedness and compactness of the weighted differentiation composition operator from weighted Bergman space to nth weighted space on the unit disk of ≤.
Zhang Liang, Zeng Hong-Gang
doaj
Fredholm Weighted Composition Operators on Dirichlet Space
International Journal of Mathematics and Mathematical Sciences, 2012 This paper characterizes bounded Fredholm, bounded invertible, and unitary weighted composition operators on Dirichlet space.
Liankuo Zhao
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Asymptotic behavior of solutions to nonlinear initial-value fractional differential problems
Electronic Journal of Differential Equations, 2016 We study the boundedness and asymptotic behavior of solutions for a class of nonlinear fractional differential equations. These equations involve two Riemann-Liouville fractional derivatives of different orders.
Mohammed D. Kassim +2 more
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Some Properties of Weighted Pseudo almost Periodic Functions
Abstract and Applied Analysis, 2013 Several interesting and new properties of weighted pseudo almost periodic functions are established. Firstly, we obtain an equivalent definition for weighted pseudo almost periodic functions, which shows a close relationship between asymptotically almost
Zhe-Ming Zheng +2 more
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Weighted Composition Groups on the Little Bloch Space
Journal of Function Spaces, 2020 Dedicated to Prof. Len Miller (PhD advisor to J. O. Bonyo) and Prof.
S. B. Mose, J. O. Bonyo
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
The weight-space of the binary perceptron
Journal of Physics A: Mathematical and General, 1993 With a view to finding features of the weight-space of the binary perceptron that might be instructive for training binary-synapse neural networks, the maximally-stable perceptron having binary-valued weights is compared with continuous-weight perceptrons, for universal choices of stored patterns. The fraction of synaptic-weights correctly predicted by
Penney, R, Sherrington, D
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