Results 121 to 130 of about 1,301,558 (327)

A permutation-based approach to inference for weighted sum regression with correlated chemical mixtures. [PDF]

Stat Methods Med Res, 2022
Lyden GR, Vock DM, Barrett ES, Sathyanarayana S, Swan SH, Nguyen RH.   +5 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Comparison of unweighted and item response theory-based weighted sum scoring for the Nine-Questions Depression-Rating Scale in the Northern Thai Dialect. [PDF]

BMC Med Res Methodol, 2022
Kawilapat S, Maneeton B, Maneeton N, Prasitwattanaseree S, Kongsuk T, Arunpongpaisal S, Leejongpermpoon J, Sukhawaha S, Traisathit P.   +8 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

On Weighted Sum Rate of Multi-User Photon-Counting Multiple-Input Multiple-Output Visible Light Communication Systems under Poisson Shot Noise

Applied Sciences
Photon counting has been proven to possess excellent signal detection capabilities at low power levels and has extensive potential applications in sixth-generation (6G) communications.
Ying Chen, Xiaolin Zhou, Jian Wang, Zhichao Dong, Yongkang Chen   +4 more
doaj   +1 more source

Prioritizing sub-watersheds for soil and water conservation via morphometric analysis and the weighted sum approach: A case study of the Geba river basin in Tigray, Ethiopia. [PDF]

Heliyon, 2022
Godif G, Manjunatha BR.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Logarithmic mean and weighted sum of geometric and anti-harmonic means

Journal of Numerical Analysis and Approximation Theory, 2012
We consider the problem of finding the optimal values \(\alpha,\ \beta\in\mathbb{R}\) for which the inequality\[\alpha G(a,b)+(1-\alpha)C(a,b)
Mira Cristiana Anisiu, Valeriu Anisiu
doaj   +2 more sources

Improved weighted sum estimation of total radiated power at W7-X

Nuclear Fusion
As magnetic confinement devices move toward higher fusion powers, moderating the heat load to the plasma-facing components becomes increasingly challenging. Efficient power dissipation can be achieved through control of the plasma radiation.
G. Partesotti, F. Reimold, A. Tsikouras, D. Zhang, G. Kawamura, B.J. Peterson, the W7-X Team   +6 more
doaj   +1 more source

Tabu search for a parallel-machine scheduling problem with periodic maintenance, job rejection and weighted sum of completion times. [PDF]

J Sched, 2022
Krim H, Zufferey N, Potvin JY, Benmansour R, Duvivier D.   +4 more
europepmc   +1 more source