Results 101 to 110 of about 17,802 (285)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Effect of weightlessness conditions on the somatic embryogenesis in the culture of carrot cells [PDF]
A carrot cell culture seeded in Petri dishes in the United States and transported to the USSR was subjected to weightlessness for 20 days during the flight of Kosmos 782.
Basyrova, L. V. +3 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Study of the astronaut's capabilities to maintain life support systems and cabin habitability in weightless conditions. Mod 3. A new technique for investigating cargo transfer in simulated weightless environments [PDF]
Simulation of cargo transfer in weightlessness ...
Loats, H. L., Jr., Mattingly, G. S.
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Research opportunities in bone demineralization, phase 3 [PDF]
Bone demineralization, calcium responses to weightlessness, endocrine responses to weightlessness, mechanisms of bone loss, biomedical research, pathogenesis, and endocrine effects are ...
Anderson, S. A., Cohn, S. H.
core +2 more sources
Weightless Infrastructures [PDF]
Organised SoundConsidered as an artistic medium, airwaves are not neutral, nor are they immaterial. The decision to broadcast is linked to the decision to activate electronic circuits. Radio holds both propagandistic and subversive potentials. But even the most experimental broad- or webcasts rely on electronic or digital technologies.
openaire +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Theoretical bases for conducting certain technological processes in space [PDF]
Dimensionless conservation equations are presented and the theoretical bases of fluid behavior aboard orbiting satellites with application to the processes of manufacturing crystals in weightlessness.
Okhotin, A. S.
core +1 more source