Results 101 to 110 of about 20,184 (348)

Effect of weightlessness conditions on the somatic embryogenesis in the culture of carrot cells [PDF]

open access: yes
A carrot cell culture seeded in Petri dishes in the United States and transported to the USSR was subjected to weightlessness for 20 days during the flight of Kosmos 782.
Basyrova, L. V.   +3 more
core   +1 more source

Functional and Structural Adaptations of Skeletal Muscle to Microgravity [PDF]

open access: yes, 2001
Our purpose is to summarize the major effects of space travel on skeletal muscle with particular emphasis on factors that alter function. The primary deleterious changes are muscle atrophy and the associated decline in peak force and power.
Fitts, Robert   +2 more
core   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Orientation in Aerospace Flight [PDF]

open access: yes
Spatial orientation and weightlessness problems in manned space ...
Graybiel, A.
core   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Rheography in weightlessness [PDF]

open access: yes
Small-scale rheographic devices for use on a space ship were developed and used during flights for the study of blood flow in vascular regions. The processes that occur during space flight and the adaptation of the human body to weightlessness are ...
Kasyan, I., Turchaninova, V.
core   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Scattering Properties of Dust Particles in Weightlessness [PDF]

open access: bronze, 1996
Jean-Claude Worms   +3 more
openalex   +1 more source

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