Results 161 to 170 of about 17,802 (285)

Space Station Centrifuge: A Requirement for Life Science Research [PDF]

A centrifuge with the largest diameter that can be accommodated on Space Station Freedom is required to conduct life science research in the microgravity environment of space.
Fuller, Charles A., Johnson, Catherine C., Smith, Arthur H., Winget, Charles M.   +3 more
core   +1 more source

Editorial: Impact of vestibular dysfunction studies on space flight health challenges. [PDF]

Front Neurol
Lackner JR, Denise P, Wood SJ.
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

M.I.T./Canadian Vestibular Experiments on the Spacelab-1 Mission. Part 1: Sensory Adaptation to Weightlessness and Readaptation to One-G: An Overview [PDF]

Experiments on human spatial orientation were conducted on four crewmembers of Space Shuttle Spacelab Mission 1. The conceptual background of the project, the relationship among the experiments, and their relevance to a 'sensory reinterpretation ...
Arrott, A. P., Kenyon, R. V., Lichtenberg, B. K., Money, K. E., Oman, C. M., Watt, D. G. D., Young, Laurence R.   +6 more
core   +1 more source

Effect of simulated microgravity via head-down tilt on intracranial compliance, brain oscillations and cardiovascular autonomic modulation. [PDF]

Sci Rep
Mendes Zambetta R, De Favari Signini É, Catai AM, Benelli A, Angius L, Dos Santos TCR, Michaliski ES, de Oliveira LB, Ocamoto GN, Santarnecchi E, Frigieri G, Russo TL.   +11 more
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

USSR Space Life Sciences Digest, issue 30 [PDF]

This is the thirtieth issue of NASA's Space Life Sciences Digest. It contains abstracts of 47 journal papers or book chapters published in Russian and of three Soviet monographs.
Rowe, Joseph, Stone, Lydia Razran, Teeter, Ronald   +2 more
core   +2 more sources

Handheld Point-of-Care Ultrasonography for Gynecology: Insights Into Space Travel Through Parabolic Flight. [PDF]

Obstet Gynecol
Mathyk B, Pandya S, Wright Beatty H, Anderson ML, Kohut A.   +4 more
europepmc   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Weightless Monuments?

, 2021
openaire   +2 more sources