Results 181 to 190 of about 25,035 (360)

Lack of response to thermal stimulation of the semicircular canals in the weightlessness phase of parabolic flight [PDF]

Caloric nystagmus response to thermal stimulation of semicircular canals in weightlessness phase of parabolic ...
Graybiel, A., Kellogg, R. S.
core   +1 more source

Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations

FEBS Open Bio, EarlyView.
We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo, Klaudia Jaczynska, Christian Rosenmund   +2 more
wiley   +1 more source

Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1926-1940, December 2022., 2022
Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh, Rachel S. Kasper, Jessie Sanford, Chia‐Ling Phuah, Jason Hassenstab, Carlos Cruchaga   +5 more
wiley   +1 more source

Formaldehyde initiates memory and motor impairments under weightlessness condition

npj Microgravity
During space flight, prolonged weightlessness stress exerts a range of detrimental impacts on the physiology and psychology of astronauts. These manifestations encompass depressive symptoms, anxiety, and impairments in both short-term memory and motor ...
Tianhao Mei, Ying Chen, Yajuan Gao, Hang Zhao, Xingzhou Lyu, Jing Lin, Tianye Niu, Hongbin Han, Zhiqian Tong   +8 more
doaj   +1 more source

EXERCISE, TEMPERATURE, AND CARDIOVASCULAR SYSTEM INTERACTION DURING SIMULATED WEIGHTLESSNESS

, 1980
W. C. Stevens, Sam Headley, A. M. Paolone   +2 more
openalex   +1 more source

Mental imagery of object motion in weightlessness [PDF]

, 2021
Silvio Gravano, Francesco Lacquaniti, Myrka Zago   +2 more
openalex   +1 more source

Comparative activity of dimethyl fumarate derivative IDMF in three models relevant to multiple sclerosis and psoriasis

FEBS Open Bio, EarlyView.
IDMF is a derivative of dimethyl fumarate (DMF) with a unique therapeutic potential at the intersection of psoriasis and multiple sclerosis. Here, we demonstrate that it compares favorably with DMF and its other derivatives, such as Diroximel, in the zebrafish, microglia, and lymphocyte models.
Yulin He, Guiyi Gong, Geovani Quijas, Simon Ming‐Yuen Lee, Ratan K. Chaudhuri, Krzysztof Bojanowski   +5 more
wiley   +1 more source

A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1985-1998, December 2022., 2022
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls, Abel Torres‐Espin, Marc Tormo, Laura Martínez‐Escardó, Núria Bonet, Ferran Casals, Xavier Navarro, Víctor J. Yuste, Esther Udina, Jordi Bruna   +9 more
wiley   +1 more source

RELATIONSHIP OF +3Gz ACCELERATION TOLERANCE TIME TO SEX, AGE, HEMODYNAMICS, SOMOTYPE, AND AEROBIC CONDITIONING BEFORE AND AFTER SIMULATED WEIGHTLESSNESS

, 1985
D. A. Ludwig, D. J. Goldwater, H. Sandler   +2 more
openalex   +1 more source

A Systems Approach to the Physiology of Weightlessness [PDF]

A systems approach to the unraveling of the complex response pattern of the human subjected to weightlessness is presented. The major goal of this research is to obtain an understanding of the role that each of the major components of the human system ...
Leach, Carolyn S., Leonard, Joel I., Rummel, John A., White, Ronald J.   +3 more
core   +1 more source