Results 191 to 200 of about 25,035 (360)
FEBS Open Bio, EarlyView.GPR142, a tryptophan‐sensing receptor, stimulates gastrointestinal hormones like ghrelin and is linked to inflammation regulation. Proinflammatory cytokines suppress ghrelin production, while tryptophan levels decrease via IDO1 activation. Our findings reveal that proinflammatory cytokines directly regulate GPR142 expression in ghrelin‐producing cells,
Yoko Ueda +15 more
wiley +1 more source
Recognizing early MRI signs (or their absence) is crucial in diagnosing metachromatic leukodystrophy
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1999-2009, December 2022., 2022 Abstract Objectives Metachromatic leukodystrophy (MLD) has characteristic white matter (WM) changes on brain MRI, which often trigger biochemical and genetic confirmation of the diagnosis. In early or pre‐symptomatic disease stages, these typical MRI changes might be absent, hampering early diagnosis.
Daphne H. Schoenmakers +7 more
wiley +1 more source
EXERCISE, TEMPERATURE, AND CARDIOVASCULAR SYSTEM INTERACTION DURING SIMULATED WEIGHTLESSNESS
, 1989 W. C. Stevens, S. Headley, A. M. Paolone
openalex +1 more source
An FPGA based Adaptive Weightless Neural Network Hardware [PDF]
, 2008 Pierre Lorrentz +2 more
openalex +1 more source
A potential tumor suppressor role of PLK2 in glioblastoma
FEBS Open Bio, EarlyView.PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia +5 more
wiley +1 more source
Space vehicle with artificial gravity and earth-like environment [PDF]
, 1973 A space vehicle adapted to provide an artificial gravity and earthlike atmospheric environment for occupants is disclosed. The vehicle comprises a cylindrically shaped, hollow pressure-tight body, one end of which is tapered from the largest diameter of ...
Gray, V. H.
core +1 more source
Identification of inhibitors of the Salmonella FraB deglycase, a drug target
FEBS Open Bio, EarlyView.A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law +6 more
wiley +1 more source
Modulation of β-adrenoceptor signaling in the hearts of 4-wk simulated weightlessness rats [PDF]
, 2008 Wen Yin +17 more
openalex +1 more source
The effect of prolonged simulated non- gravitational environment on mineral balance in the adult male, volume 1 Final report [PDF]
Effect of prolonged bed rest with simulated weightlessness on mineral balance in male adult - Vol.
Bayers, J. H. +4 more
core +1 more source