Results 41 to 50 of about 20,184 (348)
Mouse and Fly Sperm Motility Changes Differently under Modelling Microgravity
Sperm motility is essential for the natural fertilization process in most animal species. Despite the fact that evolution took place under conditions of constant gravity, the motility of spermatozoa of insects and mammals under microgravity conditions ...
Irina V. Ogneva
doaj +1 more source
Spacecraft thermal control systems based on two-phase mechanically pumped loops have advantages in terms of mass and power consumption for auxiliary needs compared to single-phase thermal control systems.
Artem Hodunov+2 more
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Chillida en América. Un encuentro con la modernidad al otro lado del Atlántico
En 1958 Eduardo Chillida recibe una beca de la Fundación Graham de Chicago en la que es alentado a profundizar en los aspectos de su trabajo más cercanos a la disciplina arquitectónica.
Pablo López-Martín
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Network topology drives population temporal variability in experimental habitat networks
Habitat patches connected by dispersal pathways form habitat networks. We explored how network topology affects population outcomes in laboratory experiments using a model species (Daphnia carinata). Central habitat nodes in complex lattice networks exhibited lower temporal variability in population sizes, suggesting they support more stable ...
Yiwen Xu+3 more
wiley +1 more source
Geographic variation in walking activity in the red flour beetle Tribolium castaneum
This study examined whether there is geographic variation in field populations, focusing on the moving activity in the red flour beetle Tribolium castaneum. Results showed significant differences in moving activity among field populations but no correlation with latitude or meteorological factors.
Kentarou Matsumura
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Cardiovascular Adaptation to Weightlessness
Exposure to actual and simulated O g causes a significant central or cephalad shift of intravascular and interstitial fluid that triggers a complex set of cardiovascular and systemic adaptations. These adaptations are, in turn, directly responsible for the cardiovascular dysfunction that is apparent after return to normal gravity.
openaire +4 more sources
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali+3 more
wiley +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
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In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
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