Results 61 to 70 of about 6,366 (302)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Simulated Weightlessness Effect on Ovarian Follicular Structure and Estradiol Levels in Rats [PDF]

Iranian South Medical Journal
Background: Long-term human habitation in space, enabled by advances in space travel, may impair the function of various physiological systems. Given the critical need to maintain astronauts’ health during and after missions, this study investigated the ...
Maryam Salavatifar, Amirreza Joorabli, Nasim Hayati Roodbari   +2 more
doaj  

Evaluation of free-floating tracheal intubation in weightlessness via ice-pick position with a direct laryngoscopy and classic approach with indirect videolaryngoscopy

npj Microgravity, 2023
Long duration spaceflights to the Moon or Mars are at risk for emergency medical events. Managing a hypoxemic distress and performing an advanced airway procedure such as oro-tracheal intubation may be complicated under weightlessness due to ergonomic ...
Séamus Thierry, François Jaulin, Clément Starck, Philippe Ariès, Jan Schmitz, Steffen Kerkhoff, Cécile Isabelle Bernard, Matthieu Komorowski, Tobias Warnecke, Jochen Hinkelbein   +9 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The Case for Bisphosphonate Use in Astronauts Flying Long-Duration Missions

Cells
Changes in the structure of bone can occur in space as an adaptive response to microgravity and on Earth due to the adaptive effects to exercise, to the aging of bone cells, or to prolonged disuse.
Reece Rosenthal, Victor S. Schneider, Jeffrey A. Jones, Jean D. Sibonga   +3 more
doaj   +1 more source

High-Throughput Sequencing Reveals CXCR4 and IGF1 Behave Different Roles in Weightlessness Osteoporosis

Stem Cells International, 2022
Objective. This study is aimed at screening the differential expression profiles of mRNA under weightlessness osteoporosis through high-throughput sequencing technology, as well as investigating the pathogenesis of weightlessness osteoporosis at the ...
Dong Wang, Weihang Li, Ziyi Ding, Quan Shi, Shilei Zhang, Zhuoru Zhang, Zhibin Liu, Xiaocheng Wang, Ming Yan   +8 more
doaj   +1 more source

Administration of Essential Phospholipids Prevents Drosophila Melanogaster Oocytes from Responding to Change in Gravity. [PDF]

Cells
The aim of this study was to prevent initial changes in Drosophila melanogaster oocytes under simulated weightlessness and hypergravity at the 2 g level.
Gogichaeva KK, Ogneva IV.
europepmc   +2 more sources

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Mental imagery of object motion in weightlessness

, 2022
dataset, articleGravano, S., Lacquaniti, F. & Zago, M. Mental imagery of object motion in weightlessness. npj Microgravity 7, 50 (2021).
Myrka Zago (565151), Silvio Gravano (10941452), Francesco Lacquaniti (150488)   +2 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source