Results 61 to 70 of about 17,802 (285)
Electromyographic analysis of skeletal muscle changes arising from 9 days of weightlessness in the Apollo-Soyuz space mission [PDF]
Both integration and frequency analyses of the electromyograms from voluntary contractions were performed in one crewman of the Apollo-Soyuz Test Project mission.
Hursta, W. N. +2 more
core +1 more source
Effects and Solutions on the Human Body After Long-Duration Space Flights [PDF]
, 2019 During the Cold War, President John F. Kennedy made it a mission for the National Aeronautics and Space Administration (NASA) to accomplish a lunar landing and return to Earth.
Esquivel Patricio, Jose Jaime
core +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Frontiers in Physiology, 2018 Estimating the effect of microgravity/hypogravity on pulmonary ventilation function remains topical. Recently developed acoustic techniques based on the evaluation of the forced expiratory noise time (FETa) were hypothesized to be a promising tool for ...
Veronika V. Malaeva +6 more
doaj +1 more source
Effects of simulated weightlessness on regional blood flow specifically during cardiovascular stress [PDF]
Significant changes in the cardiovasular system of humans and animals have been observed following exposure to prolonged periods of weightlessness during space flight.
Harrison, D. C.
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Cardiovascular Adaptation to Weightlessness
SAE Technical Paper Series, 1982 <div class="htmlview paragraph">Exposure to actual and simulated zero gravity causes a significant central or cephalad shift of intravascular and interstitial fluid which triggers a complex set of cardiovascular and systemic adaptations. These adaptations are, in turn, directly responsible for the cardiovascular dysfunction that is apparent after
openaire +3 more sources
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Materials of the final reports on the joint Soviet-American experiment on the Kosmos-936 biosatellite [PDF]
Biological experiments onboard the Kosmos-936 investigated the effect of weightlessness on the basic components of cells, the genetic structure and energy apparatus. Genetic studies were made on the Drosophila melanogaster.
Dudkin, V. Y. +9 more
core +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source