Results 71 to 80 of about 17,802 (285)
Reactivity of organism in prolonged space flights [PDF]
An analysis of published data are presented as well as the results of experiments which show that the state of weightlessness and hypodynamia result in a reduced orthostatic and vestibular resistance, increased sensitivity to infections, decreased ...
Vasilyev, P. V.
core +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Islet in weightlessness: Biological experiments on board COSMOS 1129 satellite [PDF]
Biological experiments planned as an international venture for COSMOS 1129 satellite include tests of: (1) adaptation of rats to conditions of weightlessness, and readaption to Earth's gravity; (2) possibility of fertilization and embryonic development ...
Zhuk, Y.
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Evaluation the effect of erythropoietin on osteoporosis in a microgravity simulation model [PDF]
فصلنامه ابن سینا, 2015 Background: Bone loss is a well-documented phenomenon occurring in humans both in short- and long-term spaceflights. Revealing data on the role of erythropoietin (EPO) in bone formation has led some to suggest that EPO treatment could also play a role in
A Khoshvaghti +2 more
doaj
Development program for a 200 kW, technological processes in space [PDF]
Dimensionless conservation equations, are presented and the theoretical basis of fluid behavior aboard orbiting satellites are reviewed with application to the processes of manufacturing crystals in weightlessness.
Jory, H.
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Visual and vestibular reweighting after cyber‐ and space‐sickness
Experimental PhysiologySensory conflicts are widely recognized as the primary drivers of motion sickness (MS), though the underlying integrative processes remain poorly understood. This study investigated sensory reweighting following exposure to two different sensory conflict
Tess Bonnard +4 more
doaj +1 more source
Frontiers in Physiology, 2019 Motor imagery (MI) is arguably one of the most remarkable capacities of the human mind. There is now strong experimental evidence that MI contributes to substantial improvements in motor learning and performance.
Aymeric Guillot +2 more
doaj +1 more source
Analysis of changes in leg volume parameters, and orthostatic tolerance in response to lower body negative pressure during 59 days exposure to zero gravity Skylab 3 [PDF]
The cardiovascular responses of the Apollo crewmen associated with postflight evaluations indicate varying decrements of orthostatic tolerance. The postflight changes indicate a slightly diminished ability to the cardiovascular system to function ...
Barnett, R. D. +2 more
core +1 more source