Results 71 to 80 of about 25,035 (360)

Proprioceptive disturbances in weightlessness revisited

open access: yesnpj Microgravity, 2023
AbstractThe senses of limb position and movement become degraded in low gravity. One explanation is a gravity-dependent loss of fusimotor activity. In low gravity, position and movement sense accuracy can be recovered if elastic bands are stretched across the joint.
Proske, Uwe, Weber, Bernhard
openaire   +3 more sources

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

Separator Patent [PDF]

open access: yes, 1966
Liquid-gaseous centrifugal separator for weightlessness ...
Booth, F. W.
core   +1 more source

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

High-Throughput Sequencing Reveals CXCR4 and IGF1 Behave Different Roles in Weightlessness Osteoporosis

open access: yesStem Cells International, 2022
Objective. This study is aimed at screening the differential expression profiles of mRNA under weightlessness osteoporosis through high-throughput sequencing technology, as well as investigating the pathogenesis of weightlessness osteoporosis at the ...
Dong Wang   +8 more
doaj   +1 more source

Recent results from zero g cargo handling studies [PDF]

open access: yes, 1971
Cargo handling, transfer, and stowage under weightlessness conditions of space ...
Beasley, G. P.
core   +1 more source

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

Artificial gravity as a countermeasure for mitigating physiological deconditioning during long-duration space missions

open access: yesFrontiers in Systems Neuroscience, 2015
In spite of the experience gained in human space flight since Yuri Gagarin’s historical flight in 1961, there has yet to be identified a completely effective countermeasure for mitigating the effects of weightlessness on humans. Were astronauts to embark
Gilles eClement   +2 more
doaj   +1 more source

Free Fall Frame to Demonstrate Weightlessness [PDF]

open access: yesarXiv, 2012
A simple apparatus to demonstrate free fall weightlessness is given. This can be easily constructed from readily available materials and can be used for the demonstration purpose to an audidence with all the details of the apparatus visible.
arxiv  

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