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Skeletal abnormalities in rats induced by simulated weightlessness
Metabolic Bone Disease and Related Research, 1982A hypokinetic model has been developed which attempts to simulate the weightlessness experienced during space flight. Male rats (approximately 130 g) were suspended from the model with a head-down tilt for a two-week period. Total mechanical unloading of the hind limbs and partial unloading of the fore limbs occurred.
T J, Wronski, E R, Morey
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Evaluation of the three-dimensional clinostat as a simulator of weightlessness
Planta, 1997Concerns regarding the reliability of slow-and fast-rotating uni-axial clinostats in simulating weightlessness have induced the construction of devices considered to simulate weightlessness more adequately. A new three-dimensional (3-D) clinostat equipped with two rotation axes placed at right angles has been constructed. In the clinostat, the rotation
T, Hoson +4 more
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Simulated weightlessness for the ontogenesis of the otolith organ
Die Naturwissenschaften, 1968Abstract : The critical phase of the otolith-organ-ripening within the embryo was used in a simulation experiment by setting frog eggs (Rana temporaria) and toad eggs (Bufo bufo) near the center of a rotating system with a horizontal axis. The experiment speeds were 100 and 160 r.p.m.; the eggs and tadpoles were subjected to maximal centripetal forces ...
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Human Autonomic Responses to Actual and Simulated Weightlessness
The Journal of Clinical Pharmacology, 1991Orthostatic dysfunction occurs after exposure to microgravity, and is not completely understood. The authors developed a device for stimulating carotid baroreceptors to test the hypothesis that exposure to microgravity leads to impairment of arterial baroreflex mechanisms.
D L, Eckberg, J M, Fritsch
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Effects of Simulated Weightlessness on Bone Mineral Metabolism
Endocrinology, 1984Space flight and bedrest result in a negative calcium balance and osteopenia. The mechanisms underlying these events are not well understood. In particular, it is not clear whether systemic or local factors are preeminent in mediating the effects of gravity on bone mineral content.
R K, Globus, D D, Bikle, E, Morey-Holton
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[Weightlessness or weightlessness simulation and vascular remodeling].
Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering, 2003Weightlessness is inavoidable during spaceflight. It brings profound physiological effects on human body. Vascular remodeling is one of the important changes of cardiovascular system caused by weightlessness or simulated weightlessness. The paper summarized the studies on the effects of weightlessness or weightlessness simulation on vascular remodeling
Yong, Yue +3 more
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Simulated Weightlessness in the Design and Exploitation of a NMR-Compatible Bioreactor
Biotechnology Progress, 2004Mammalian cells cultured in simulated weightlessness take advantage of a favorable environment, experiencing low shear stress and reduced turbulence. NMR spectroscopy allows the on-line noninvasive monitoring of cell growth and metabolism. With this in mind, we developed a novel bioreactor that fits into a NMR instrument and in which the simulated ...
Bradamante S, Barenghi L, Villa A
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1986
The phenomenon of gravitation is characterized by the mutual attraction of any two bodies. The universal character of gravitation was first recognized by Isaac Newton who found the well-known law for the attraction force F acting between two mass points or homogeneous spherical bodies $$\rm F\, = \,\gamma Mm/R^2 $$ (3.1) M, m are the masses ...
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The phenomenon of gravitation is characterized by the mutual attraction of any two bodies. The universal character of gravitation was first recognized by Isaac Newton who found the well-known law for the attraction force F acting between two mass points or homogeneous spherical bodies $$\rm F\, = \,\gamma Mm/R^2 $$ (3.1) M, m are the masses ...
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[Changes of leg compliance during weightlessness or simulated weightlessness].
Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering, 2002Weightlessness or simulated weightlessness causes increase of leg compliance. It leads to more blood pooling in the legs and less blood returning to the heart during orthostatic test, which may partly explain the occurrence of orthostatic intolerance induced by weightlessness or simulated weightlessness.
Wen-bin, Liang +2 more
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[Mechanism of cardiac atrophy under weightlessness/simulated weightlessness].
Sheng li xue bao : [Acta physiologica Sinica], 2017Cardiac remodeling is the heart's response to external or internal stimuli. Weightlessness/simulated weightlessness leads to cardiac atrophy and heart function declining. Understanding the mechanism of cardiac atrophy under weightlessness is important to help astronaut recover from unloading-induced cardiovascular changes after spaceflight.
Guo-Hui, Zhong +2 more
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