Results 181 to 190 of about 1,127,856 (277)

Privacy and personalisation: predicting Parkinson's disease severity from real-world gait with federated learning. [PDF]

Front Aging Neurosci
Hinchliffe C, Hiden H, Alcock L, Lawson RA, Yarnall AJ, Rochester L, Del Din S, Watson P.   +7 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

The development of a performance evaluation index system for internet hospitals in Qingdao, China: A Delphi consensus study. [PDF]

SAGE Open Med
Cui N, Sun J, Sui X, Ma P, Sun J, Baloch Z, Cui J.   +6 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Work-active ageing or healthy worker selection? Late-life employment and happiness among older migrants in Europe. [PDF]

J Migr Health
Ugwu LE, Ugwoke UF, Ramonkga BN, Okonkwo AE, Ramadie KJ.   +4 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

An improved Newman fast division algorithm based on multi-factor correlation for dynamic traffic sub-region control. [PDF]

PLoS One
Tian X, Ding J, Liu H, Deng H.
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Advanced Sensitive Feature Machine Learning for Aesthetic Evaluation Prediction of Industrial Products. [PDF]

J Imaging
Ouyang J, Xi Z, Su J, Zhang S, Hu Y, Zhou A.   +5 more
europepmc   +1 more source